Benzene

Benzene

SCHEMBL8992260

[SiH3].c1ccccc1.c1ccccc1

nearest known ligand 0.75

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.75
TP53 P04637 1/20 0.75
ALDH1A1 P00352 1/20 0.30
NAPRT Q6XQN6 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL8992291 0.89
Benzene SCHEMBL11504534 0.89 TP53 (0.60) TSHRTP53
Benzene SCHEMBL702735 0.89 TP53 (0.60) TSHRTP53
Benzene SCHEMBL11765474 0.89 TSHR (0.60) TSHRTP53NAPRTTDP1
Benzene SCHEMBL8430159 0.87 TSHR (1.00) TSHRTP53ALDH1A1NAPRTTDP1
Benzene SCHEMBL8576855 0.87 TSHR (1.00) TSHRTP53ALDH1A1NAPRTTDP1
Benzene SCHEMBL8107103 0.87 TSHR (1.00) TSHRTP53ALDH1A1NAPRTTDP1
SCHEMBL1086976 0.87 TSHR (1.00) TSHRTP53ALDH1A1NAPRTTDP1
SCHEMBL1112772 0.87 TSHR (1.00) TSHRTP53ALDH1A1NAPRTTDP1
Benzene SCHEMBL10780001 0.87 TSHR (1.00) TSHRTP53ALDH1A1NAPRTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5516871-A Diphenylsiloxane oligomers functionalized at both terminals and methods for the preparation thereof DOW CORNING ASIA, LTD. (JP) 1996-05-14 US claimed
US-5502229-A ENDCAPPING DOW CORNING ASIA, LTD. (JP) 1996-03-26 US claimed
US-5516871-A Diphenylsiloxane oligomers functionalized at both terminals and methods for the preparation thereof DOW CORNING ASIA, LTD. (JP) 1996-05-14 US disclosed
US-5502229-A ENDCAPPING DOW CORNING ASIA, LTD. (JP) 1996-03-26 US disclosed