Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.63 |
| ▸ | RARA | P10276 | 1/20 | 0.63 |
| ▸ | RARG | P13631 | 1/20 | 0.63 |
| ▸ | PPARA | Q07869 | 2/20 | 0.57 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
| ▸ | THRA | P10827 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.46 |
| ▸ | TACR2 | P21452 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3281472 | 0.89 | RARB (0.78) | RARBRARARARGPPARAKAT8 | |
| SCHEMBL28260247 | 0.89 | RARB (0.78) | RARBRARARARGPPARAKAT8 | |
| SCHEMBL15583717 | 0.89 | RARB (0.61) | RARBRARARARGPPARAKAT8 | |
| SCHEMBL3281551 | 0.89 | RARB (0.78) | RARBRARARARGPPARAKAT8 | |
| SCHEMBL9238571 | 0.87 | RARB (0.76) | RARBRARARARGPPARAKAT8 | |
| SCHEMBL16684105 | 0.87 | MAOB (0.51) | RARBRARARARGPPARAMAOB | |
| SCHEMBL10460146 | 0.86 | RARB (0.62) | RARBRARARARGPPARAKAT8 | |
| SCHEMBL20476364 | 0.84 | RARB (0.59) | RARBRARARARGPPARAKAT8 | |
| SCHEMBL23891741 | 0.83 | RARB (0.54) | RARBRARARARGPPARAKAT8 | |
| SCHEMBL9767995 | 0.83 | PPARA (0.77) | RARBRARARARGPPARAKAT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433826-B1 | Fluorophenylpyridines | HOECHST AG (DE) | 1996-07-10 | — | — | EP | disclosed |
| US-5204476-A | For use in chiral tilted smectic liquid crystal phases | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-04-20 | — | — | US | disclosed |
| EP-0433826-A2 | Fluorophenylpyridines | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-06-26 | — | — | EP | disclosed |