Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2611009 | 0.80 | MEN1 (0.42) | MEN1KMT2AKDM4ECHRM2CHRM4 | |
| SCHEMBL21192211 | 0.76 | CHRM2 (0.43) | MEN1KMT2AKDM4ECHRM2CHRM4 | |
| SCHEMBL10257125 | 0.73 | CHRM2 (0.59) | MEN1KMT2AKDM4ECHRM2CHRM4 | |
| SCHEMBL23863480 | 0.71 | MEN1 (0.40) | MEN1KMT2AKDM4ECHRM2CHRM4 | |
| SCHEMBL5158331 | 0.71 | — | — | |
| SCHEMBL25819543 | 0.70 | CHRM2 (0.37) | MEN1KMT2AKDM4ECHRM2CHRM4 | |
| SCHEMBL3989603 | 0.69 | — | — | |
| SCHEMBL21192215 | 0.69 | CHRM2 (0.40) | MEN1KMT2AKDM4ECHRM2CHRM4 | |
| SCHEMBL9474332 | 0.67 | CHRM2 (0.48) | MEN1KMT2AKDM4ECHRM2CHRM4 | |
| SCHEMBL10271777 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445749-B1 | N-Monosubstituted cyclopentenylamines, a process for their preparation and their use as medicaments | FUJISAWA PHARMACEUTICAL CO (JP) | 1996-07-10 | — | — | EP | disclosed |
| US-5256824-A | Anticholinergic agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-10-26 | — | — | US | disclosed |
| EP-0445749-A1 | N-Monosubstituted cyclopentenylamines, a process for their preparation and their use as medicaments | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-09-11 | — | — | EP | disclosed |