Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | VDR | P11473 | 8/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8992724 | 1.00 | CYP19A1 (0.39) | CYP19A1VDR | |
| SCHEMBL8993014 | 0.89 | CYP19A1 (0.37) | CYP19A1VDR | |
| SCHEMBL8993016 | 0.89 | CYP19A1 (0.37) | CYP19A1VDR | |
| SCHEMBL8992696 | 0.87 | CYP19A1 (0.36) | CYP19A1VDR | |
| SCHEMBL8992693 | 0.87 | CYP19A1 (0.36) | CYP19A1VDR | |
| SCHEMBL8992745 | 0.83 | CYP19A1 (0.36) | CYP19A1 | |
| SCHEMBL8992748 | 0.83 | CYP19A1 (0.36) | CYP19A1 | |
| SCHEMBL8992723 | 0.81 | CYP19A1 (0.34) | CYP19A1 | |
| SCHEMBL8992719 | 0.81 | CYP19A1 (0.34) | CYP19A1 | |
| SCHEMBL1039872 | 0.80 | CYP19A1 (0.45) | CYP19A1VDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5585368-A | SKIN DISORDERS | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-12-17 | — | — | US | disclosed |
| EP-0647219-B1 | DERIVATIVES IN THE VITAMIN D SERIES MODIFIED AT THE 20 POSITION, A METHOD OF PREPARING SUCH DERIVATIVES, INTERMEDIATES USED IN THIS METHOD, PHARMACEUTICAL PREPARATIONS CONTAINING THE DERIVATIVES AND THEIR USE IN THE PREPARATION OF DRUGS | SCHERING AG (DE) | 1996-07-31 | — | — | EP | disclosed |