SCHEMBL8992802

SCHEMBL8992802

Cc1ccc(Cc2ccc(CO)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 1/20 0.50
IDO1 P14902 2/20 0.46
ESR1 P03372 2/20 0.43
ESR2 Q92731 2/20 0.43
TSHR P16473 1/20 0.43
CYP1A2 P05177 1/20 0.42
CYP2A6 P11509 1/20 0.42
TAAR1 Q96RJ0 1/20 0.42
ACHE P22303 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
HDAC8 Q9BY41 1/20 0.41
AGXT P21549 2/20 0.41
KMT2A Q03164 1/20 0.41
MAP2K4 P45985 1/20 0.41
LTA4H P09960 1/20 0.40
NOS3 P29474 1/20 0.40
NOS1 P29475 1/20 0.40
PRSS1 P07477 1/20 0.39
PRSS2 P07478 1/20 0.39
PRSS3 P35030 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17742723 0.93 SRD5A2 (0.46) SRD5A2IDO1ESR1ESR2TSHR
SCHEMBL21114374 0.92 IDO1 (0.52) IDO1TSHRCYP1A2CYP2A6TAAR1
SCHEMBL3337 0.92
Ammonia Solution, Strong SCHEMBL28235889 0.89 IDO1 (0.50) IDO1TSHRCYP1A2CYP2A6TAAR1
SCHEMBL586331 0.89 IDO1 (0.50) IDO1TSHRCYP1A2CYP2A6TAAR1
Methane SCHEMBL27627149 0.89 IDO1 (0.50) IDO1TSHRCYP1A2CYP2A6TAAR1
SCHEMBL585056 0.89 IDO1 (0.50) IDO1TSHRCYP1A2CYP2A6TAAR1
SCHEMBL586153 0.89 IDO1 (0.50) IDO1TSHRCYP1A2CYP2A6TAAR1
Alcohol SCHEMBL1568943 0.86 IDO1 (0.48) IDO1TSHRCYP1A2CYP2A6TAAR1
SCHEMBL260498 0.86 TSHR (0.56) ESR1ESR2TSHRTDP1HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180157139-A1 ELECTROCHEMICAL ENERGY STORAGE DEVICES GENTEX CORPORATION 2018-06-07 US disclosed
US-9964828-B2 Electrochemical energy storage devices GENTEX CORPORATION (US) 2018-05-08 US disclosed
US-9696623-B2 Photosensitive compositions and applications thereof PROMERUS, LLC (US) 2017-07-04 US disclosed
US-20160223908-A1 PHOTOSENSITIVE COMPOSITIONS AND APPLICATIONS THEREOF PROMERUS, LLC (US) 2016-08-04 US disclosed
EP-2042312-B1 Processing method of lithographic printing plate precursor FUJIFILM CORP (JP) 2016-05-18 EP disclosed
US-9341949-B2 Photosensitive compositions and applications thereof PROMERUS, LLC (US) 2016-05-17 US disclosed
US-20150346573-A1 ELECTROCHEMICAL ENERGY STORAGE DEVICES GENTEX CORPORATION 2015-12-03 US disclosed
US-20140322647-A1 PHOTOSENSITIVE COMPOSITIONS AND APPLICATIONS THEREOF SUMITOMO BAKELITE CO., LTD (JP) 2014-10-30 US disclosed
US-5516777-A PROSTATE CANCER THERAPY OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1996-05-14 US disclosed
US-5409928-A Prostate diseases, alopecia OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1995-04-25 US disclosed
EP-0594149-A2 Condensed pyrazole derivatives, method of manufacturing the same, and androgen inhibitor OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1994-04-27 EP disclosed