Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP2 | O95551 | 3/20 | 0.39 |
| ▸ | NSD2 | O96028 | 3/20 | 0.39 |
| ▸ | APAF1 | O14727 | 2/20 | 0.39 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GALK1 | P51570 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Triaziquone SCHEMBL7088197 | 1.00 | DNMT1 (0.47) | DNMT1MAPTHTTTP53STAT3 | |
| Triaziquone SCHEMBL1334390 | 0.98 | DNMT1 (0.46) | DNMT1MAPTHTTTP53STAT3 | |
| Triaziquone SCHEMBL8303 | 0.98 | DNMT1 (0.48) | DNMT1MAPTHTTTP53STAT3 | |
| Triaziquone SCHEMBL1538515 | 0.95 | DNMT1 (0.47) | DNMT1MAPTHTTTP53STAT3 | |
| Triaziquone SCHEMBL5054475 | 0.95 | DNMT1 (0.47) | DNMT1MAPTHTTTP53STAT3 | |
| Triaziquone SCHEMBL8482641 | 0.95 | DNMT1 (0.47) | DNMT1MAPTHTTTP53STAT3 | |
| Triaziquone SCHEMBL3101456 | 0.95 | DNMT1 (0.47) | DNMT1MAPTHTTTP53STAT3 | |
| Triaziquone SCHEMBL7738777 | 0.95 | DNMT1 (0.47) | DNMT1MAPTHTTTP53STAT3 | |
| Triaziquone SCHEMBL6000230 | 0.95 | DNMT1 (0.47) | DNMT1MAPTHTTTP53STAT3 | |
| Triaziquone SCHEMBL9876358 | 0.95 | DNMT1 (0.47) | DNMT1MAPTHTTTP53STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292689-B1 | Substituted 1,4,7-triscarboxymethyl-1,4,7,10-tetraazacyclo-dodecane and analogs | BRACCO INT BV (NL) | 1996-07-31 | — | — | EP | disclosed |
| EP-0292689-A2 | Substituted 1,4,7-triscarboxymethyl-1,4,7,10-tetraazacyclo-dodecane and analogs | BRACCO INTERNATIONAL B.V. (NL) | 1988-11-30 | — | — | EP | disclosed |