Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | GSK3A | P49840 | 2/20 | 0.43 |
| ▸ | GSK3B | P49841 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GSR | P00390 | 1/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9114814 | 0.86 | MCHR1 (0.47) | SMN1; SMN2LMNAHTTALDH1A1MAPT | |
| SCHEMBL7846203 | 0.85 | GSK3A (0.37) | GSK3AGSK3BHTTALDH1A1KMT2A | |
| SCHEMBL8700806 | 0.85 | GSK3A (0.37) | GSK3AGSK3BHTTALDH1A1ALOX15 | |
| SCHEMBL7888772 | 0.85 | GSK3A (0.40) | GSK3AGSK3BLMNAALDH1A1KMT2A | |
| SCHEMBL7887352 | 0.85 | GSK3A (0.43) | GSK3AGSK3BALDH1A1KMT2ATSHR | |
| SCHEMBL13693064 | 0.83 | PTGS1 (0.37) | POLBMAPTNPSR1NOTUM | |
| SCHEMBL7557543 | 0.82 | GSK3A (0.46) | SMN1; SMN2GSK3AGSK3BLMNAHTT | |
| SCHEMBL31442410 | 0.82 | COMT (0.37) | SMN1; SMN2GSK3AGSK3BALDH1A1KMT2A | |
| SCHEMBL7833205 | 0.82 | MEN1 (0.41) | GSK3AGSK3BHTTALDH1A1ALOX15 | |
| SCHEMBL7929163 | 0.82 | NOTUM (0.33) | GSK3AGSK3BMAPTNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5527764-A | 3-arylthionouracils useful as herbicides, defoliants, and desiccants | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1996-06-18 | — | — | US | disclosed |
| WO-1996008477-A1 | 3-ARYLTHIONOURACILS USEFUL AS HERBICIDES, DEFIOLANTS, AND DESICCANTS | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1996-03-21 | — | — | WO | disclosed |