Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.59 |
| ▸ | PPARA | Q07869 | 2/20 | 0.59 |
| ▸ | TTR | P02766 | 5/20 | 0.58 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.58 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.58 |
| ▸ | DPP4 | P27487 | 1/20 | 0.56 |
| ▸ | APP | P05067 | 10/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | GMNN | O75496 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | FYN | P06241 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8993664 | 1.00 | PPARG (0.59) | PPARGPPARATTRAKR1B10AKR1B1 | |
| SCHEMBL3219707 | 0.88 | PPARG (0.63) | PPARGPPARATTRAKR1B10AKR1B1 | |
| SCHEMBL3219709 | 0.88 | PPARG (0.63) | PPARGPPARATTRAKR1B10AKR1B1 | |
| SCHEMBL8993585 | 0.88 | PPARG (0.68) | PPARGPPARATTRAKR1B1HSD17B10 | |
| SCHEMBL8993581 | 0.88 | PPARG (0.68) | PPARGPPARATTRAKR1B1HSD17B10 | |
| SCHEMBL18204462 | 0.85 | KDM4E (0.57) | PPARGPPARAAPPKDM4EALDH1A1 | |
| SCHEMBL18204463 | 0.85 | KDM4E (0.57) | PPARGPPARAAPPKDM4EALDH1A1 | |
| SCHEMBL29403744 | 0.85 | KDM4E (0.57) | PPARGPPARAAPPKDM4EALDH1A1 | |
| SCHEMBL7633899 | 0.82 | PPARG (0.59) | PPARGPPARAKDM4E | |
| SCHEMBL7633917 | 0.82 | PPARG (0.59) | PPARGPPARAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8012664-A | — | — | None | — | — | JP | disclosed |
| US-5486624-A | FREE RADICAL SCAVENGERS, TYROSINASE INHIBITORS | PACIFIC CORPORATION (KR) | 1996-01-23 | — | — | US | disclosed |
| JP-H0812664-A | KOJIC ACID DERIVATIVE | PACIFIC CORP | 1996-01-16 | — | — | JP | disclosed |