SCHEMBL8993742

SCHEMBL8993742

CCOC(=O)C(Cc1ccc(C(=N)N)cc1)n1cccc(NS(=O)(=O)c2ccc3ccccc3c2)c1=O

nearest known ligand 0.49

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PLG P00747 6/20 0.49
F2 P00734 8/20 0.48
PRSS1 P07477 6/20 0.48
F10 P00742 5/20 0.48
PLAU P00749 2/20 0.46
PLAT P00750 1/20 0.46
PRSS2 P07478 3/20 0.46
PRSS3 P35030 3/20 0.46
ST14 Q9Y5Y6 2/20 0.46
HPN P05981 1/20 0.45
SLC16A3 O15427 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8993773 0.90 SLC16A3 (0.48) PLGF2PRSS1F10PLAU
SCHEMBL8993740 0.77 F2 (0.58) PLGF2PRSS1F10PLAU
SCHEMBL8993694 0.76 F2 (0.61) PLGF2PRSS1F10PLAU
Acetic Acid SCHEMBL6032662 0.72 F2 (0.52) F2PRSS1F10PRSS2PRSS3
SCHEMBL8993681 0.70 F10 (0.69) PLGF2PRSS1F10PLAT
SCHEMBL8993718 0.70 F10 (0.67) PLGF2PRSS1F10PLAT
SCHEMBL8993723 0.69 F10 (0.65) PLGF2PRSS1F10PLAT
SCHEMBL8993840 0.69 F10 (0.59) PLGF2PRSS1F10PLAT
SCHEMBL8993733 0.69 F10 (0.63) PLGF2PRSS1F10PLAT
SCHEMBL9710389 0.69 F2 (0.70) PLGF2F10PLAUST14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5489583-A FOR TREATING OR PREVENTING THROMBOSIS BASF AKTIENGESELLSCHAFT (DE) 1996-02-06 US disclosed