SCHEMBL8993759

SCHEMBL8993759

CCOC(=O)C(Cc1ccc(C(=N)N)cc1)N1CCC(NS(=O)(=O)c2ccc3cc4c(cc3c2)OCO4)C1=O

nearest known ligand 0.54

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
F10 P00742 19/20 0.54
F2 P00734 10/20 0.49
PRSS1 P07477 3/20 0.48
PLG P00747 2/20 0.48
PROC P04070 2/20 0.48
PLAT P00750 1/20 0.48
PRSS2 P07478 1/20 0.48
PRSS3 P35030 1/20 0.48
F9 P00740 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8993823 0.96 F10 (0.51) F10F2PRSS1PLGPROC
SCHEMBL8993711 0.91 F10 (0.54) F10F2PRSS1PLGPROC
SCHEMBL8993740 0.90 F2 (0.58) F10F2PRSS1PLGPROC
SCHEMBL8993840 0.90 F10 (0.59) F10F2PRSS1PLGPROC
SCHEMBL8993681 0.89 F10 (0.69) F10F2PRSS1PLGPROC
SCHEMBL8993718 0.89 F10 (0.67) F10F2PRSS1PLGPROC
SCHEMBL8993807 0.87 F10 (0.57) F10F2PRSS1PLGPROC
SCHEMBL8993765 0.87 F2 (0.54) F10F2PRSS1PLGPROC
SCHEMBL8993694 0.86 F2 (0.61) F10F2PRSS1PLGPROC
SCHEMBL8993753 0.85 F10 (0.56) F10F2PRSS1PLGPROC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5489583-A FOR TREATING OR PREVENTING THROMBOSIS BASF AKTIENGESELLSCHAFT (DE) 1996-02-06 US disclosed