Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Ammonia Solution, Strong. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL10950233 | 0.94 | — | — | |
| Lithium Ion SCHEMBL26914837 | 0.94 | MEN1 (0.75) | — | |
| Lithium Ion SCHEMBL22864 | 0.94 | — | — | |
| Ammonia Solution, Strong SCHEMBL193771 | 0.88 | MEN1 (0.67) | — | |
| Lithium Ion SCHEMBL8505025 | 0.88 | MEN1 (0.67) | — | |
| Lithium Ion SCHEMBL23753488 | 0.88 | — | — | |
| Water SCHEMBL7857556 | 0.88 | MEN1 (0.67) | — | |
| Ammonia Solution, Strong SCHEMBL4814853 | 0.88 | — | — | |
| Ammonia Solution, Strong SCHEMBL7556202 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL23243661 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5582020-A | Chemical/mechanical system and method using two-phase/two-component compression heat pump | MAINSTREAM ENGINEERING CORPORATION (US) | 1996-12-10 | — | — | US | claimed |
| US-10845100-B2 | Low-power absorption refrigeration machine | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (ES) | 2020-11-24 | — | — | US | disclosed |
| US-20170153046-A1 | Low-Power Absorption Refrigeration Machine | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (ES) | 2017-06-01 | — | — | US | disclosed |
| EP-3150940-A1 | LOW-POWER ABSORPTION REFRIGERATOR MACHINE | Consejo Superior De Investigaciones Científicas (CSIC) (ES) | 2017-04-05 | — | — | EP | disclosed |
| US-5582020-A | Chemical/mechanical system and method using two-phase/two-component compression heat pump | MAINSTREAM ENGINEERING CORPORATION (US) | 1996-12-10 | — | — | US | disclosed |
| CN-1095813-A | Compressing-absorbing complex circulating refrigeration system | LIANG MINGCHU (CN) | 1994-11-30 | — | — | CN | disclosed |