Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 20/20 | 0.71 |
| ▸ | PIK3CD | O00329 | 19/20 | 0.71 |
| ▸ | PIK3R1 | P27986 | 19/20 | 0.71 |
| ▸ | PIK3CB | P42338 | 15/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL477551 | 0.93 | PIK3CA (0.64) | PIK3CAPIK3CDPIK3R1PIK3CB | |
| SCHEMBL899080 | 0.92 | PIK3CA (0.72) | PIK3CAPIK3CDPIK3R1PIK3CB | |
| SCHEMBL29358094 | 0.91 | PIK3CA (0.73) | PIK3CAPIK3CDPIK3R1PIK3CB | |
| SCHEMBL477656 | 0.91 | PIK3CA (0.73) | PIK3CAPIK3CDPIK3R1PIK3CB | |
| SCHEMBL16429406 | 0.89 | PIK3CA (0.71) | PIK3CAPIK3CDPIK3R1PIK3CB | |
| SCHEMBL477550 | 0.87 | PIK3CA (0.68) | PIK3CAPIK3CDPIK3R1PIK3CB | |
| SCHEMBL477673 | 0.85 | PIK3CB (0.77) | PIK3CAPIK3CDPIK3R1PIK3CB | |
| SCHEMBL477736 | 0.83 | PIK3CB (0.80) | PIK3CAPIK3CDPIK3R1PIK3CB | |
| SCHEMBL477982 | 0.83 | PIK3CA (0.71) | PIK3CAPIK3CDPIK3R1PIK3CB | |
| SCHEMBL899653 | 0.83 | PIK3CD (1.00) | PIK3CAPIK3CDPIK3R1PIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012044641-A1 | 1,3,5-TRIAZINYL BENZIMIDAZOLE SULFONAMIDES AND THEIR USE IN CANCER THERAPY | PATHWAY THERAPEUTICS INC. (US) | 2012-04-05 | — | — | WO | claimed |
| WO-2012044641-A1 | 1,3,5-TRIAZINYL BENZIMIDAZOLE SULFONAMIDES AND THEIR USE IN CANCER THERAPY | PATHWAY THERAPEUTICS INC. (US) | 2012-04-05 | — | — | WO | disclosed |
| WO-2012044641-A1 | 1,3,5-TRIAZINYL BENZIMIDAZOLE SULFONAMIDES AND THEIR USE IN CANCER THERAPY | PATHWAY THERAPEUTICS INC. (US) | 2012-04-05 | — | — | WO | disclosed |