Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL1271252 | 1.00 | — | — | |
| Bicarbonate SCHEMBL28822774 | 1.00 | CA1 (0.83) | — | |
| Bicarbonate SCHEMBL1091168 | 1.00 | — | — | |
| Bicarbonate SCHEMBL29679 | 1.00 | — | — | |
| Bicarbonate SCHEMBL9769208 | 0.93 | — | — | |
| Bicarbonate SCHEMBL14562675 | 0.93 | — | — | |
| Bicarbonate SCHEMBL408951 | 0.93 | — | — | |
| Bicarbonate SCHEMBL1887321 | 0.93 | — | — | |
| Bicarbonate SCHEMBL22806874 | 0.93 | — | — | |
| Bicarbonate SCHEMBL8038412 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5507862-A | PROTECTIVE COATINGS CONTAINING SUBSTITUTED N-PHENYLISOTHIAZOLONES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-04-16 | — | — | US | claimed |