Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | TGM2 | P21980 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | UBE2I | P63279 | 1/20 | 0.40 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.40 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | FPR2 | P25090 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6984911 | 0.86 | CYP2C19 (0.41) | CYP2C19MAPTCA12CA9GAA | |
| SCHEMBL9980454 | 0.81 | GAA (0.45) | CYP2C19MAPTRAB9ANPSR1MITF | |
| SCHEMBL4974275 | 0.81 | GAA (0.45) | CYP2C19MAPTRAB9ANPSR1MITF | |
| SCHEMBL7875843 | 0.78 | FOLH1 (0.40) | CYP2C19TGM2MAPTGAAPOLB | |
| SCHEMBL1128808 | 0.78 | FOLH1 (0.40) | CYP2C19TGM2MAPTGAAPOLB | |
| SCHEMBL344918 | 0.77 | MME (0.45) | MAPTRAB9ANPSR1LMNACA12 | |
| SCHEMBL3488827 | 0.77 | MME (0.45) | MAPTRAB9ANPSR1LMNACA12 | |
| SCHEMBL344919 | 0.77 | MME (0.45) | MAPTRAB9ANPSR1LMNACA12 | |
| SCHEMBL11345309 | 0.77 | CYP2C19 (0.46) | CYP2C19TGM2MAPTRAB9ANPSR1 | |
| SCHEMBL12637385 | 0.77 | CYP2C19 (0.54) | CYP2C19MAPTLMNAPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0494716-B1 | Enzyme-catalysed preparation of optically active carboxylic acids | DSM NV (NL) | 1996-08-28 | — | — | EP | disclosed |
| US-5248608-A | Enzyme catalyzed stereospecific hdyrolysis | DSM N.V. (NL) | 1993-09-28 | — | — | US | disclosed |
| EP-0494716-A2 | Enzyme-catalysed preparation of optically active carboxylic acids | DSM N.V. (NL) | 1992-07-15 | — | — | EP | disclosed |