Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 13/20 | 0.77 |
| ▸ | ERBB2 | P04626 | 5/20 | 0.77 |
| ▸ | MEN1 | O00255 | 4/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.77 |
| ▸ | MAPT | P10636 | 3/20 | 0.77 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.77 |
| ▸ | LMNA | P02545 | 2/20 | 0.77 |
| ▸ | TP53 | P04637 | 2/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.77 |
| ▸ | HPGD | P15428 | 2/20 | 0.77 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.77 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.77 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.77 |
| ▸ | BLM | P54132 | 2/20 | 0.77 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.77 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8996081 | 0.87 | EGFR (0.77) | EGFRERBB2MEN1KMT2AALDH1A1 | |
| SCHEMBL28558448 | 0.87 | EGFR (0.77) | EGFRERBB2MEN1KMT2AALDH1A1 | |
| SCHEMBL28558447 | 0.87 | EGFR (0.77) | EGFRERBB2MEN1KMT2AALDH1A1 | |
| SCHEMBL29766990 | 0.87 | EGFR (1.00) | EGFRERBB2MEN1KMT2AALDH1A1 | |
| SCHEMBL1704988 | 0.87 | EGFR (1.00) | EGFRERBB2MEN1KMT2AALDH1A1 | |
| SCHEMBL30555674 | 0.87 | EGFR (1.00) | EGFRERBB2MEN1KMT2AALDH1A1 | |
| SCHEMBL5909179 | 0.87 | EGFR (1.00) | EGFRERBB2MEN1KMT2AALDH1A1 | |
| SCHEMBL8996037 | 0.86 | EGFR (0.76) | EGFRERBB2MEN1KMT2AALDH1A1 | |
| SCHEMBL28552134 | 0.81 | EGFR (0.67) | EGFRERBB2MEN1KMT2AALDH1A1 | |
| SCHEMBL8995995 | 0.79 | EGFR (0.76) | EGFRERBB2MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537742-B1 | Styrene derivatives | MITSUBISHI CHEM CORP (JP) | 1996-08-21 | — | — | EP | disclosed |
| US-5514711-A | ANTICARCINOGENIC AGENTS; SIDE EFFECT REDUCTION | MITSUBISHI CHEMICAL CORPORATION (JP) | 1996-05-07 | — | — | US | disclosed |
| EP-0537742-A2 | Styrene derivatives | Mitsubishi Chemical Corporation (JP) | 1993-04-21 | — | — | EP | disclosed |