Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | GBA1 | P04062 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL538540 | 1.00 | POLB (0.59) | POLBMEN1KMT2AHRH3GBA1 | |
| SCHEMBL538541 | 1.00 | POLB (0.59) | POLBMEN1KMT2AHRH3GBA1 | |
| SCHEMBL15669880 | 0.98 | POLB (0.57) | POLBMEN1KMT2AHRH3GBA1 | |
| SCHEMBL1897843 | 0.98 | POLB (0.57) | POLBMEN1KMT2AHRH3GBA1 | |
| SCHEMBL23802807 | 0.98 | POLB (0.57) | POLBMEN1KMT2AHRH3GBA1 | |
| SCHEMBL23802919 | 0.98 | POLB (0.57) | POLBMEN1KMT2AHRH3GBA1 | |
| Bromide SCHEMBL15670016 | 0.95 | POLB (0.55) | POLBMEN1KMT2AHRH3 | |
| SCHEMBL10981485 | 0.86 | MEN1 (0.47) | POLBMEN1KMT2AHRH3 | |
| SCHEMBL28311651 | 0.85 | POLB (0.50) | POLBMEN1KMT2AGBA1 | |
| SCHEMBL16738 | 0.83 | POLB (0.58) | POLBMEN1KMT2AHRH3GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116239476-A | Preparation method of selegiline hydrochloride isomer | 安徽贝克制药股份有限公司 | 2023-06-09 | — | — | CN | disclosed |
| CN-110655466-B | Preparation method of benzphetamine hydrochloride | 安徽贝克制药股份有限公司 | 2023-02-24 | — | — | CN | disclosed |
| CN-110668952-A | Preparation method of benzphetamine hydrochloride | 安徽贝克联合制药有限公司 | 2020-01-10 | — | — | CN | disclosed |
| CN-110655466-A | Preparation method of benzphetamine hydrochloride | 安徽贝克联合制药有限公司 | 2020-01-07 | — | — | CN | disclosed |
| WO-2012045007-A1 | METHOD OF PREPARATION OF (4 - {4 -ACETYLAMINO- 2 - [3- ( 2 - ISOPROPYL - THIAZOL - 4 - YLMETHYL) - 3 -METHYL - UREIDO] - BUTYRYL AMINO} -1 -BENZYL- 5 -PHENYL- PENTYL) -CARBAMIC ACID THIAZOL - 5 - YLMETHYL ESTER | GILEAD SCIENCES, INC. (US) | 2012-04-05 | — | — | WO | disclosed |
| WO-2012045007-A1 | METHOD OF PREPARATION OF (4 - {4 -ACETYLAMINO- 2 - [3- ( 2 - ISOPROPYL - THIAZOL - 4 - YLMETHYL) - 3 -METHYL - UREIDO] - BUTYRYL AMINO} -1 -BENZYL- 5 -PHENYL- PENTYL) -CARBAMIC ACID THIAZOL - 5 - YLMETHYL ESTER | GILEAD SCIENCES, INC. (US) | 2012-04-05 | — | — | WO | disclosed |