Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | UBE2N | P61088 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10394316 | 0.79 | HSD17B2 (0.51) | HSD17B2GAAMAPTTSHRALDH1A1 | |
| SCHEMBL10394100 | 0.77 | HSD17B2 (0.46) | HSD17B2GAAMAPTCYP3A4UBE2N | |
| SCHEMBL2806526 | 0.74 | PTPN11 (0.47) | HSD17B2PTPN11GAAMAPTTSHR | |
| SCHEMBL10394356 | 0.74 | HSD17B2 (0.43) | HSD17B2GAACYP3A4UBE2NALDH1A1 | |
| SCHEMBL4647233 | 0.72 | HSD17B2 (0.66) | HSD17B2GAAMAPTTSHRALDH1A1 | |
| SCHEMBL24073868 | 0.71 | HSD17B2 (0.44) | HSD17B2PTPN11GAAMAPTCYP3A4 | |
| SCHEMBL10393725 | 0.71 | HSD17B2 (0.47) | HSD17B2GAACYP3A4UBE2NALDH1A1 | |
| SCHEMBL2807973 | 0.71 | TSHR (0.45) | HSD17B2PTPN11GAAMAPTCYP3A4 | |
| SCHEMBL26412235 | 0.71 | HTT (0.45) | HSD17B2MAPTTSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL1846303 | 0.70 | KDM4E (0.47) | HSD17B2GAAMAPTTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5480873-A | ARTHRITIS | LILLY INDUSTRIES LIMITED (GB) | 1996-01-02 | — | — | US | disclosed |
| EP-0570091-A1 | Anthraquinone derivatives, process for their preparation and their use as medicaments | LILLY INDUSTRIES LIMITED (GB) | 1993-11-18 | — | — | EP | disclosed |