SCHEMBL8996553

SCHEMBL8996553

N=Cc1csc2ccccc12

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 3/20 0.64
MAPT P10636 3/20 0.49
ALDH1A1 P00352 3/20 0.49
TDP1 Q9NUW8 2/20 0.49
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
PKM P14618 2/20 0.49
KDM4E B2RXH2 1/20 0.49
KDM4C Q9H3R0 1/20 0.49
PTGS1 P23219 1/20 0.46
PTGS2 P35354 1/20 0.46
TUBB4A P04350 1/20 0.44
TUBB P07437 1/20 0.44
TUBA3C P0DPH7 1/20 0.44
TUBA1B P68363 1/20 0.44
TUBA4A P68366 1/20 0.44
TUBB4B P68371 1/20 0.44
TUBB3 Q13509 1/20 0.44
TUBB2A Q13885 1/20 0.44
TUBB8 Q3ZCM7 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15930269 0.78 CYP2A6 (0.64) CYP2A6MAPTALDH1A1TDP1MEN1
SCHEMBL40953 0.78 CYP2A6 (1.00) CYP2A6MAPTALDH1A1TDP1MEN1
SCHEMBL80050 0.78 CYP2A6 (0.64) CYP2A6MAPTALDH1A1TDP1MEN1
SCHEMBL11708827 0.78 CYP2A6 (0.64) CYP2A6MAPTALDH1A1TDP1MEN1
SCHEMBL30076672 0.78 CYP2A6 (1.00) CYP2A6MAPTALDH1A1TDP1MEN1
SCHEMBL9729987 0.75 CYP2A6 (0.60) CYP2A6MAPTALDH1A1TDP1MEN1
SCHEMBL7974567 0.75 CYP2A6 (0.92) CYP2A6MAPTALDH1A1TDP1MEN1
SCHEMBL17742294 0.75 CYP2A6 (0.60) CYP2A6MAPTALDH1A1TDP1MEN1
SCHEMBL5360487 0.75 CYP2A6 (0.60) CYP2A6MAPTALDH1A1TDP1MEN1
SCHEMBL3080071 0.75 CYP2A6 (0.60) CYP2A6MAPTALDH1A1TDP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5547980-A ANTIALLERGENS, BRONCHODILATOR BOEHRINGER MANNHEIM GMBH (DE) 1996-08-20 US disclosed