SCHEMBL8996670

SCHEMBL8996670

CCCCCC1CC(N)CC(CCCCC)N1

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
S1PR2 O95136 2/20 0.43
S1PR4 O95977 2/20 0.43
S1PR1 P21453 2/20 0.43
S1PR3 Q99500 2/20 0.43
S1PR5 Q9H228 2/20 0.43
SPHK1 Q9NYA1 5/20 0.38
ALDH1A1 P00352 2/20 0.35
GLB1 P16278 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
GBA1 P04062 4/20 0.34
SPHK2 Q9NRA0 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7524719 0.84
SCHEMBL9070519 0.81 S1PR2 (0.48) S1PR2S1PR4S1PR1S1PR3S1PR5
Ammonia Solution, Strong SCHEMBL27996193 0.79 S1PR2 (0.47) S1PR2S1PR4S1PR1S1PR3S1PR5
SCHEMBL13939571 0.77 S1PR2 (0.46) S1PR2S1PR4S1PR1S1PR3S1PR5
Ammonia Solution, Strong SCHEMBL27996175 0.77 S1PR2 (0.42) S1PR2S1PR4S1PR1S1PR3S1PR5
SCHEMBL5362759 0.77 S1PR2 (0.63) S1PR2S1PR4S1PR1S1PR3S1PR5
SCHEMBL19527212 0.76 S1PR2 (0.44) S1PR2S1PR4S1PR1S1PR3S1PR5
Ammonia Solution, Strong SCHEMBL28099882 0.76 S1PR2 (0.41) S1PR2S1PR4S1PR1S1PR3S1PR5
SCHEMBL24059097 0.75 S1PR2 (0.41) S1PR2S1PR4S1PR1S1PR3S1PR5
SCHEMBL24053264 0.75 CYP1A2 (0.41) SPHK1ALDH1A1SPHK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0512948-B1 Substituted 1-hydroxy-2,6-Di-aryl-4-acyloxypiperidines or 1-hydroxy-2,6-diaryl-4-acyl-aminopiperidines and stabilized compositions CIBA GEIGY AG (CH) 1996-08-28 EP disclosed
US-5371125-A Process stabilizers; discoloration inhibition; oxidation and heat resistance CIBA-GEIGY CORPORATION (US) 1994-12-06 US disclosed
US-5262538-A Stabilizers for heat, oxidation and radiation resistance CIBA-GEIGY CORPORATION (US) 1993-11-16 US disclosed
US-5180829-A Stabilizers against oxygen, heat and actinic radiation CIBA-GEIGY CORPORATION (US) 1993-01-19 US disclosed
EP-0512948-A1 Substituted 1-hydroxy-2,6-Di-aryl-4-acyloxypiperidines or 1-hydroxy-2,6-diaryl-4-acyl-aminopiperidines and stabilized compositions CIBA-GEIGY AG (CH) 1992-11-11 EP disclosed