Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIP4K2C | Q8TBX8 | 19/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL901247 | 0.80 | PIP4K2C (1.00) | PIP4K2CHTTPAX8 | |
| SCHEMBL900498 | 0.78 | PIP4K2C (1.00) | PIP4K2C | |
| SCHEMBL14965845 | 0.78 | SMN1; SMN2 (0.70) | PIP4K2CHTTPAX8 | |
| SCHEMBL900003 | 0.78 | PIP4K2C (1.00) | PIP4K2CHTTPAX8 | |
| SCHEMBL903157 | 0.78 | PIP4K2C (1.00) | PIP4K2C | |
| SCHEMBL903108 | 0.78 | PIP4K2C (0.79) | PIP4K2C | |
| SCHEMBL903171 | 0.78 | PIP4K2C (0.89) | PIP4K2C | |
| SCHEMBL900551 | 0.77 | PIP4K2C (1.00) | PIP4K2CHTTPAX8 | |
| SCHEMBL903163 | 0.77 | PIP4K2C (1.00) | PIP4K2CHTTPAX8 | |
| SCHEMBL2368374 | 0.77 | SMN1; SMN2 (0.77) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012044993-A1 | COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF TREATING OR PREVENTING NEURODEGENERATIVE DISEASES OR DISORDERS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2012-04-05 | — | — | WO | disclosed |
| WO-2012044993-A1 | COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF TREATING OR PREVENTING NEURODEGENERATIVE DISEASES OR DISORDERS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2012-04-05 | — | — | WO | disclosed |