Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 6/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.42 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.42 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.42 |
| ▸ | ALB | P02768 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 3/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8997068 | 1.00 | NR1I2 (0.43) | NR1I2HTR2CKMT2APTGS1ABCB11 | |
| SCHEMBL8996820 | 0.98 | NR1I2 (0.43) | NR1I2HTR2CKMT2APTGS1ABCB11 | |
| SCHEMBL8996830 | 0.94 | NR1I2 (0.38) | NR1I2HTR2CKMT2APTGS1ABCB11 | |
| SCHEMBL8996827 | 0.94 | NR1I2 (0.38) | NR1I2HTR2CKMT2APTGS1ABCB11 | |
| SCHEMBL8996993 | 0.92 | NR1I2 (0.37) | NR1I2HTR2CKMT2APTGS1ABCB11 | |
| SCHEMBL8996884 | 0.91 | NR1I2 (0.43) | NR1I2HTR2CKMT2APTGS1ABCB11 | |
| SCHEMBL8996906 | 0.91 | NR1I2 (0.43) | NR1I2HTR2CKMT2APTGS1ABCB11 | |
| SCHEMBL8996799 | 0.91 | NR1I2 (0.44) | NR1I2HTR2CKMT2APTGS1ABCB11 | |
| SCHEMBL8997038 | 0.91 | PTGS1 (0.48) | NR1I2HTR2CKMT2APTGS1ABCB11 | |
| SCHEMBL8997034 | 0.91 | PTGS1 (0.48) | NR1I2HTR2CKMT2APTGS1ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0432042-B1 | Cephalosporin derivatives and their production and uses | MEIJI SEIKA KAISHA (JP) | 1996-08-28 | — | — | EP | disclosed |
| US-5332731-A | Antibiotics as bactericides | MEIJI SEIKA KAISHA, LTD. (JP) | 1994-07-26 | — | — | US | disclosed |
| EP-0432042-A2 | Cephalosporin derivatives and their production and uses | MEIJI SEIKA KAISHA LTD. (JP) | 1991-06-12 | — | — | EP | disclosed |