Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PRKCA | P17252 | 1/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8997866 | 0.80 | CA1 (0.43) | KMT2ATDP1TSHRCYP2D6HTT | |
| SCHEMBL8997763 | 0.80 | CA1 (0.43) | KMT2ATDP1TSHRCYP2D6HTT | |
| SCHEMBL8997936 | 0.78 | TDP1 (0.37) | KMT2ATDP1TSHRHTTSLC1A1 | |
| SCHEMBL7990400 | 0.77 | SLC6A2 (0.51) | KMT2ASLC6A2SLC6A3TDP1TP53 | |
| SCHEMBL10590715 | 0.75 | SLC6A2 (0.49) | KMT2ASLC6A2SLC6A3TDP1TP53 | |
| SCHEMBL16429136 | 0.73 | CA1 (0.43) | KMT2ATSHRCYP2D6HTTSLC1A1 | |
| SCHEMBL9837867 | 0.73 | CA1 (0.43) | KMT2ATSHRCYP2D6HTTSLC1A1 | |
| SCHEMBL10507146 | 0.72 | SLC1A3 (0.45) | KMT2ASLC6A2SLC6A3TDP1TSHR | |
| SCHEMBL19592303 | 0.72 | KMT2A (0.40) | KMT2ASLC6A2SLC6A3TDP1TP53 | |
| SCHEMBL14429223 | 0.72 | HTT (0.43) | KMT2ATDP1TSHRCYP2D6HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5521163-A | TREATMENT OF HERPES VIRUS WITH 1'-DEOXY-5-ETHYL-4'-THIO-BETA URIDINE | UNIVERSITY OF BIRMINGHAM (GB) | 1996-05-28 | — | — | US | disclosed |
| US-5356882-A | Treating herpes virus | UNIVERSITY OF BIRMINGHAM (GB) | 1994-10-18 | — | — | US | disclosed |
| WO-1991001326-A1 | ANTIVIRAL PYRIMIDINE NUCLEOSIDES | UNIVERSITY OF BIRMINGHAM (GB) | 1991-02-07 | — | — | WO | disclosed |