Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.58 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | IKBKB | O14920 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 8/20 | 0.46 |
| ▸ | RAB9A | P51151 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8997922 | 1.00 | NPC1 (0.60) | NPC1ALDH1A1HSD11B1EGFRIKBKB | |
| SCHEMBL8882040 | 0.84 | AKR1C3 (0.57) | NPC1ALDH1A1EGFRMAPTRAB9A | |
| SCHEMBL8852927 | 0.84 | AKR1C3 (0.57) | NPC1ALDH1A1EGFRMAPTRAB9A | |
| SCHEMBL8145324 | 0.84 | AKR1C3 (0.57) | NPC1ALDH1A1EGFRMAPTRAB9A | |
| SCHEMBL3437935 | 0.84 | HPGD (0.61) | NPC1ALDH1A1EGFRMAPTRAB9A | |
| SCHEMBL3437937 | 0.84 | HPGD (0.61) | NPC1ALDH1A1EGFRMAPTRAB9A | |
| SCHEMBL8675213 | 0.84 | HPGD (0.61) | NPC1ALDH1A1EGFRMAPTRAB9A | |
| SCHEMBL8883417 | 0.80 | AKR1C3 (0.55) | NPC1ALDH1A1EGFRMAPTRAB9A | |
| SCHEMBL8883420 | 0.80 | AKR1C3 (0.55) | NPC1ALDH1A1EGFRMAPTRAB9A | |
| SCHEMBL5169484 | 0.77 | HSP90AA1 (0.63) | NPC1ALDH1A1HSD11B1EGFRIKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523303-A | ANTIULCER AND -SECRETORY AGENTS; GASTRIC H+K+ ATPASE INHIBITORS; NONTOXIC; OXIMES DERIVATIVES | EGIS GYOGYSZERGYAR RT. (HU) | 1996-06-04 | — | — | US | disclosed |