SCHEMBL8997938

SCHEMBL8997938

O=C(O)C(S)CCC(CO)(CO)CO

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RNPEP Q9H4A4 3/20 0.50
FOLH1 Q04609 1/20 0.50
HPGD P15428 2/20 0.33
HSD17B10 Q99714 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
ABCB11 O95342 1/20 0.33
F2 P00734 1/20 0.33
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
ALOX15 P16050 1/20 0.33
KMT2A Q03164 1/20 0.33
DUSP3 P51452 1/20 0.33
PTPN5 P54829 1/20 0.33
PTPN11 Q06124 1/20 0.33
LMNA P02545 1/20 0.33
CYP2C9 P11712 1/20 0.33
HIF1A Q16665 1/20 0.33
CPB2 Q96IY4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9464054 0.78 FOLH1 (0.46) RNPEPFOLH1HPGDHSD17B10TDP1
SCHEMBL10577283 0.77 RNPEP (0.47) RNPEPFOLH1TDP1ALDH1A1MAPT
SCHEMBL3796923 0.76 FOLH1 (0.68) RNPEPFOLH1HPGDHSD17B10TDP1
SCHEMBL931181 0.76 FOLH1 (0.68) RNPEPFOLH1HPGDHSD17B10TDP1
SCHEMBL3077756 0.74 RNPEP (0.43) RNPEPFOLH1HPGDHSD17B10TDP1
SCHEMBL3094996 0.74 RNPEP (0.43) RNPEPFOLH1HPGDHSD17B10TDP1
SCHEMBL10580605 0.74 RNPEP (0.44) RNPEPFOLH1TDP1ALDH1A1MAPT
SCHEMBL10579184 0.74 RNPEP (0.48) RNPEPFOLH1TDP1MAPT
SCHEMBL2770550 0.74 TDP1 (0.40) RNPEPFOLH1HPGDHSD17B10TDP1
SCHEMBL902699 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5574117-A SULFUR COMPOUND NIPPON SHOKUBAI CO., LTD. (JP) 1996-11-12 US disclosed