Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 15/20 | 0.82 |
| ▸ | SRC | P12931 | 9/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1191332 | 0.81 | KDM4E (0.69) | EGFRSRCKDM4ELMNAALDH1A1 | |
| SCHEMBL27191679 | 0.79 | EGFR (0.68) | EGFRSRCATMKDM4ELMNA | |
| SCHEMBL14367892 | 0.79 | EGFR (0.68) | EGFRSRC | |
| SCHEMBL3276728 | 0.78 | EGFR (0.66) | EGFRSRCKDM4ELMNAALDH1A1 | |
| SCHEMBL28518839 | 0.78 | EGFR (0.66) | EGFRSRCCHRNA7KDM4ELMNA | |
| SCHEMBL7905354 | 0.78 | EGFR (0.66) | EGFRKDM4ELMNAALDH1A1HSD17B10 | |
| SCHEMBL13246948 | 0.77 | EGFR (0.64) | EGFRSRCATMKDM4ELMNA | |
| SCHEMBL5972910 | 0.76 | EGFR (0.63) | EGFRSRCCHRNA7KDM4ELMNA | |
| SCHEMBL24098781 | 0.75 | EGFR (0.61) | EGFRSRCKDM4EALDH1A1MAPT | |
| SCHEMBL30325227 | 0.75 | EGFR (0.61) | EGFRSRCKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5556874-A | ENZYME INHIBITORS AS ANTICARCINOGENIC AGENTS | WARNER LAMBERT COMPANY (US) | 1996-09-17 | — | — | US | claimed |