Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 1/20 | 0.45 |
| ▸ | CHKA | P35790 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.35 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9662918 | 0.91 | RARB (0.51) | RARBCHKAPDK2CNR1CNR2 | |
| SCHEMBL9664422 | 0.91 | RARB (0.51) | RARBCHKAPDK2CNR1CNR2 | |
| SCHEMBL8507964 | 0.89 | RARB (0.46) | RARBCHKACNR1CNR2MAOB | |
| SCHEMBL9399967 | 0.89 | RARB (0.52) | RARBCHKAPDK2CNR1CNR2 | |
| SCHEMBL16377224 | 0.87 | RARB (0.51) | RARBCHKAPDK2CNR1CNR2 | |
| SCHEMBL8999654 | 0.86 | RARB (0.46) | RARBCHKAPDK2CNR1CNR2 | |
| SCHEMBL8857691 | 0.86 | RARB (0.45) | RARBCHKACNR1CNR2MAOB | |
| SCHEMBL9664434 | 0.86 | RARB (0.48) | RARBCHKAPDK2CNR1CNR2 | |
| SCHEMBL8378004 | 0.86 | RARB (0.48) | RARBCHKACNR1CNR2MAOB | |
| SCHEMBL9663386 | 0.86 | RARB (0.48) | RARBCHKAPDK2CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0449288-B1 | Phenylethanes and liquid crystal medium | MERCK PATENT GMBH (DE) | 1996-09-11 | — | — | EP | disclosed |
| EP-0449288-A2 | Phenylethanes and liquid crystal medium | MERCK PATENT GmbH (DE) | 1991-10-02 | — | — | EP | disclosed |