Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 4/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8561219 | 0.96 | TSHR (0.55) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL8855874 | 0.96 | TSHR (0.55) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL7737199 | 0.92 | TSHR (0.46) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL31150912 | 0.92 | TSHR (0.49) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL7567268 | 0.90 | TSHR (0.73) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL313059 | 0.89 | TSHR (0.76) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL9319734 | 0.87 | TSHR (0.65) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL263473 | 0.86 | TSHR (0.67) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL28682532 | 0.86 | TSHR (0.67) | TSHRHPGDALDH1A1CYP3A4THRB | |
| Acrylic Acid Methyl Ester SCHEMBL28097602 | 0.86 | TSHR (0.67) | TSHRHPGDALDH1A1CYP3A4THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5567761-A | BLEND OF ACETOACETYLATED POLYMER AND A POLYACRYLATE; GLOSS, HARDNESS | GUERTIN BROS. COATINGS AND SEALANTS LTD. (CA) | 1996-10-22 | — | — | US | disclosed |
| WO-1995016749-A1 | AQUEOUS TWO-PART ISOCYANATE-FREE CURABLE, POLYURETHANE RESIN SYSTEMS | GUERTIN BROS. COATINGS AND SEALANTS LTD. (CA) | 1995-06-22 | — | — | WO | disclosed |