SCHEMBL9000656

SCHEMBL9000656

CCCCCC(CO)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CERT1 Q9Y5P4 3/20 0.44
CSNK1E P49674 1/20 0.42
OPRM1 P35372 2/20 0.42
OPRD1 P41143 2/20 0.42
OPRK1 P41145 2/20 0.42
OPRL1 P41146 2/20 0.42
LMNA P02545 2/20 0.42
SIGMAR1 Q99720 1/20 0.42
NAAA Q02083 2/20 0.41
POLB P06746 1/20 0.41
NR1I2 O75469 1/20 0.41
CNR2 P34972 1/20 0.41
CYSLTR2 Q9NS75 1/20 0.41
CYSLTR1 Q9Y271 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28139983 1.00 CERT1 (0.44) CERT1CSNK1EOPRM1OPRD1OPRK1
SCHEMBL27299340 0.98 CERT1 (0.47) CERT1CSNK1EOPRM1OPRD1OPRK1
SCHEMBL27674519 0.98 CERT1 (0.47) CERT1CSNK1EOPRM1OPRD1OPRK1
SCHEMBL17027703 0.98 CERT1 (0.47) CERT1CSNK1EOPRM1OPRD1OPRK1
SCHEMBL17027860 0.98 CERT1 (0.47) CERT1CSNK1EOPRM1OPRD1OPRK1
SCHEMBL10940817 0.98 CERT1 (0.47) CERT1CSNK1EOPRM1OPRD1OPRK1
SCHEMBL10905725 0.98 CERT1 (0.47) CERT1CSNK1EOPRM1OPRD1OPRK1
SCHEMBL500649 0.98 CERT1 (0.47) CERT1CSNK1EOPRM1OPRD1OPRK1
SCHEMBL821043 0.94 POLB (0.46) CERT1OPRM1OPRD1OPRK1OPRL1
SCHEMBL22808422 0.94 POLB (0.46) CERT1OPRM1OPRD1OPRK1OPRL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106535866-B E isomer-enriched mixtures of musk compounds having an unsaturated macrocyclic ring 西姆莱斯有限公司 2020-05-15 CN disclosed
US-5583147-A INHIBITORS OF ACYL-COENZYME A: CHOLESTEROL O-TRANSFERASE; ANTIHYPERCHOLESTEROLEMIC AND/OR ANTIATHEROSCLEROTIC AGENTS THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) 1996-12-10 US disclosed