Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RARB | P10826 | 3/20 | 0.45 |
| ▸ | CETP | P11597 | 2/20 | 0.45 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.45 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.45 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9001548 | 0.89 | MAPT (0.58) | MAPTTP53RXFP1THRBKDM4E | |
| SCHEMBL8307428 | 0.87 | MAPT (0.58) | MAPTTP53RXFP1THRBP2RY14 | |
| SCHEMBL8308595 | 0.86 | RARB (0.62) | MAPTTP53RXFP1THRBTSHR | |
| SCHEMBL7333665 | 0.86 | RARB (0.62) | MAPTTP53RXFP1THRBTSHR | |
| SCHEMBL9001558 | 0.84 | ESR1 (0.60) | MAPTTP53RXFP1THRBCHRNB4 | |
| SCHEMBL8307382 | 0.83 | MAPT (0.54) | MAPTTP53RXFP1THRBRARB | |
| SCHEMBL8306605 | 0.83 | MAPT (0.54) | MAPTTP53RXFP1THRBKDM4E | |
| SCHEMBL9001546 | 0.83 | SMN1; SMN2 (0.62) | MAPTTP53RXFP1THRBKDM4E | |
| SCHEMBL7606471 | 0.82 | MAPT (0.55) | MAPTTP53RXFP1THRBHSD17B10 | |
| SCHEMBL9001581 | 0.81 | MAPT (0.53) | MAPTTP53RXFP1THRBP2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0460703-B1 | Mesomorphic compound, liquid crystal composition, liquid crystal device, display apparatus and display method | CANON KK (JP) | 1996-09-04 | — | — | EP | disclosed |
| US-5318720-A | Liquid crystal composition, liquid crystal device, display apparatus and display method | CANON KABUSHIKI KAISHA (JP) | 1994-06-07 | — | — | US | disclosed |
| EP-0460703-A1 | Mesomorphic compound, liquid crystal composition, liquid crystal device, display apparatus and display method | CANON KABUSHIKI KAISHA (JP) | 1991-12-11 | — | — | EP | disclosed |