SCHEMBL9001674

SCHEMBL9001674

O=P(O)(O)/C(=C\c1ccccc1)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C1 Q04828 1/20 0.48
PRMT1 Q99873 1/20 0.44
ALDH1A1 P00352 2/20 0.42
LMNA P02545 2/20 0.42
MAPT P10636 2/20 0.42
KDM4E B2RXH2 1/20 0.42
MEN1 O00255 1/20 0.42
POLB P06746 1/20 0.42
HPGD P15428 1/20 0.42
MAPK1 P28482 1/20 0.42
HTT P42858 1/20 0.42
KMT2A Q03164 1/20 0.42
TSHR P16473 2/20 0.41
DAO P14920 1/20 0.41
NAPRT Q6XQN6 1/20 0.41
AKR1C3 P42330 1/20 0.41
NR1I2 O75469 1/20 0.41
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
ESR1 P03372 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1579379 1.00 AKR1C1 (0.48) AKR1C1PRMT1ALDH1A1LMNAMAPT
SCHEMBL15768786 0.87 SRD5A2 (0.52) AKR1C1ALDH1A1LMNAMAPTMEN1
SCHEMBL14681172 0.82 AKR1C1 (0.47) AKR1C1PRMT1ALDH1A1LMNAMAPT
SCHEMBL7616389 0.80 AKR1C1 (0.46) AKR1C1PRMT1ALDH1A1LMNAMAPT
SCHEMBL7616394 0.80 AKR1C1 (0.46) AKR1C1PRMT1ALDH1A1LMNAMAPT
SCHEMBL28838094 0.79 KMT2A (0.62) ALDH1A1LMNAMAPTMEN1POLB
SCHEMBL28838095 0.79 KMT2A (0.55) ALDH1A1LMNAMAPTMEN1POLB
SCHEMBL11031402 0.78 TSHR (0.44) ALDH1A1LMNAKDM4EMEN1POLB
SCHEMBL11031403 0.78 TSHR (0.44) ALDH1A1LMNAKDM4EMEN1POLB
SCHEMBL14198473 0.77 AKR1C1 (0.43) AKR1C1PRMT1ALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5457163-A Using styrene, divinylbenzene, and bis(2-chloroethyl)vinyl-phosphonate KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1995-10-10 US claimed
CN-112126212-B Phosphorus-containing resin composition and articles made therefrom 台光电子材料股份有限公司 2022-12-06 CN disclosed
WO-2022202743-A1 MONOMER MIXTURE, RESIN COMPOSITION, RESIN MOLDED ARTICLE, PANEL FOR AQUARIUMS, ILLUMINATED SIGN, BUILDING COMPONENT, METHOD FOR PRODUCING RESIN COMPOSITION, AND METHOD FOR MANUFACTURING RESIN CAST BOARD 三菱ケミカル株式会社 2022-09-29 WO disclosed
CN-112126212-A Phosphorus-containing resin composition and articles made therefrom 台光电子材料股份有限公司 2020-12-25 CN disclosed
CN-106085169-B Curable composition 味之素株式会社 2020-12-18 CN disclosed
US-5489616-A COPOLYMERIZING, PHOSPHONATION, HYDROLYSIS, OXIDATION; REUSABLE KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1996-02-06 US disclosed
US-5457163-A Using styrene, divinylbenzene, and bis(2-chloroethyl)vinyl-phosphonate KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1995-10-10 US disclosed