SCHEMBL9002281

SCHEMBL9002281

CC(C)(C)c1cc(-n2n3c4ccccc4n23)c(O)c(C(C)(C)C)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 2/20 0.46
▸ CYP1A2 P05177 1/20 0.46
▸ CYP3A4 P08684 1/20 0.46
▸ CYP2C9 P11712 1/20 0.46
▸ CYP2C19 P33261 1/20 0.46
▸ ALOX5 P09917 3/20 0.39
▸ PTGS2 P35354 3/20 0.39
▸ HSP90AA1 P07900 1/20 0.38
▸ CA2 P00918 3/20 0.37
▸ CA1 P00915 1/20 0.37
▸ F2R P25116 3/20 0.37
▸ HPN P05981 1/20 0.37
▸ MAPT P10636 1/20 0.37
▸ ALOX15 P16050 1/20 0.37
▸ SIRT5 Q9NXA8 1/20 0.37
▸ ALDH1A1 P00352 3/20 0.36
▸ POLB P06746 1/20 0.36
▸ TYR P14679 1/20 0.36
▸ SMN1; SMN2 Q16637 1/20 0.36
▸ TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13652814 0.88 CYP3A4 (0.39) TSHRCYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL12733195 0.87 HSPA5 (0.44) TSHRCYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL12774894 0.87 TSHR (0.41) TSHRCYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL13245893 0.84 SMN1; SMN2 (0.53) TSHRCYP1A2CYP2C9CYP2C19ALOX5
SCHEMBL9002268 0.84 CYP1A2 (0.35) TSHRCYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL9002272 0.84 CYP2C9 (0.35) TSHRCYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL12733208 0.80 HSPA5 (0.54) TSHRCYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL12733192 0.80 HSPA5 (0.57) TSHRCYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL2612593 0.80 ESR1 (0.42) TSHRCYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL13223584 0.80 HSPA5 (0.50) TSHRCYP1A2CYP3A4CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9726932-B2 Optical film, optical compensation film, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2017-08-08 — — US disclosed
US-9726932-B2 Optical film, optical compensation film, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2017-08-08 — — US disclosed
US-20160231606-A1 OPTICAL FILM, OPTICAL COMPENSATION FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY FUJIFILM CORPORATION (JP) 2016-08-11 — — US disclosed
US-20160231606-A1 OPTICAL FILM, OPTICAL COMPENSATION FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY FUJIFILM CORPORATION (JP) 2016-08-11 — — US disclosed
US-9354356-B2 Polymer film, and optically-compensatory film, polarizer and liquid-crystal display device comprising the same FUJIFILM CORPORATION (JP) 2016-05-31 — — US disclosed
US-9354356-B2 Polymer film, and optically-compensatory film, polarizer and liquid-crystal display device comprising the same FUJIFILM CORPORATION (JP) 2016-05-31 — — US disclosed
US-9348177-B2 Optical film, optical compensation film, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2016-05-24 — — US disclosed
US-9348177-B2 Optical film, optical compensation film, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2016-05-24 — — US disclosed
US-9195090-B2 Polymer film, optically-compensatory film, process for producing the same, polarizing plate and liquid-crystal display device FUJIFILM CORPORATION (JP) 2015-11-24 — — US disclosed
US-9195090-B2 Polymer film, optically-compensatory film, process for producing the same, polarizing plate and liquid-crystal display device FUJIFILM CORPORATION (JP) 2015-11-24 — — US disclosed
WO-2007037540-A9 CELLULOSE ACYLATE FILM, METHOD FOR PRODUCING SAME, OPTICALLY COMPENSATORY FILM, ANTI-REFLECTION FILM, POLARIZING PLATE AND IMAGE DISPLAY DEVICE FUJIFILM CORP (JP) 2007-05-31 — — WO disclosed
US-20070076155-A1 Optical film, optical compensation film, polarizing plate and liquid crystal display FUJI PHOTO FILM CO., LTD. (JP) 2007-04-05 — — US disclosed
WO-2007037540-A1 CELLULOSE ACYLATE FILM, METHOD FOR PRODUCING SAME, OPTICALLY COMPENSATORY FILM, ANTI-REFLECTION FILM, POLARIZING PLATE AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2007-04-05 — — WO disclosed
US-7192904-B2 Thermal recording material FUJI PHOTO FILM CO., LTD. (JP) 2007-03-20 — — US disclosed
US-7192904-B2 Thermal recording material FUJI PHOTO FILM CO., LTD. (JP) 2007-03-20 — — US disclosed
US-20070059458-A1 Cellulose acylate film, optically compensatory film, polarizing plate and liquid crystal display FUJI PHOTO FILM CO., LTD. (JP) 2007-03-15 — — US disclosed
US-20070048458-A1 Optical film, method of producing the same, optical compensatory film, polarizing film, and liquid crystal display device FUJI PHOTO FILM CO., LTD. (JP) 2007-03-01 — — US disclosed
US-20070040962-A1 Optical resin film and polarizing plate and liquid crystal display using same FUJI PHOTO FILM CO., LTD. (JP) 2007-02-22 — — US disclosed
US-7160840-B2 Thermal recording material FUJI PHOTO FILM CO., LTD. (JP) 2007-01-09 — — US disclosed
US-7160840-B2 Thermal recording material FUJI PHOTO FILM CO., LTD. (JP) 2007-01-09 — — US disclosed
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