Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 14/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | IL2RA | P01589 | 1/20 | 0.33 |
| ▸ | ALB | P02768 | 1/20 | 0.33 |
| ▸ | IL2 | P60568 | 1/20 | 0.33 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7391272 | 0.97 | F2 (0.40) | F2ALDH1A1IL2RAALBIL2 | |
| Acetic Acid SCHEMBL9003102 | 0.89 | F2 (0.39) | F2ALDH1A1IL2RAALBIL2 | |
| Acetic Acid SCHEMBL9002747 | 0.88 | F2 (0.38) | F2ALDH1A1IL2RAALBIL2 | |
| Acetic Acid SCHEMBL9002876 | 0.88 | F2 (0.44) | F2ALDH1A1IL2RAALBIL2 | |
| SCHEMBL9002970 | 0.87 | F2 (0.40) | F2ALDH1A1IL2RAALBIL2 | |
| Acetic Acid SCHEMBL9002983 | 0.87 | F2 (0.39) | F2PRSS1 | |
| Hydrochloric Acid SCHEMBL9002899 | 0.86 | F2 (0.41) | F2PSMB5PRSS1 | |
| SCHEMBL7395161 | 0.86 | F2 (0.40) | F2IL2RAALBIL2PSMB5 | |
| SCHEMBL7395152 | 0.86 | F2 (0.40) | F2ALDH1A1IL2RAALBIL2 | |
| Acetic Acid SCHEMBL9002993 | 0.86 | F2 (0.44) | F2PSMB5PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5559232-A | ANTICOAGULANTS | HOFFMANN-LA ROCHE INC. (US) | 1996-09-24 | — | — | US | disclosed |