SCHEMBL9002803

SCHEMBL9002803

CCCCN(CC(=O)O)C(=O)C(CC(=O)NC[C@H]1CN(C=NN)CCO1)NC(=O)OCc1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.39
SIRT2 Q8IXJ6 9/20 0.38
SIRT1 Q96EB6 5/20 0.38
CTSS P25774 3/20 0.38
CTSL P07711 1/20 0.38
BCHE P06276 1/20 0.37
ACHE P22303 1/20 0.37
TGM2 P21980 1/20 0.36
SIRT3 Q9NTG7 4/20 0.35
CTSK P43235 3/20 0.35
CTSB P07858 2/20 0.35
CASP1 P29466 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9003074 0.99 CYP1A2 (0.39) CYP1A2SIRT2SIRT1CTSSCTSL
SCHEMBL7393199 0.95 CYP1A2 (0.39) CYP1A2SIRT2SIRT1CTSSCTSL
SCHEMBL7396489 0.91 BCHE (0.40) CYP1A2SIRT2SIRT1CTSSCTSL
Hydrochloric Acid SCHEMBL9002723 0.91 BCHE (0.40) CYP1A2SIRT2SIRT1CTSSCTSL
SCHEMBL9002811 0.88 BCHE (0.40) SIRT2SIRT1CTSSCTSLBCHE
Hydrochloric Acid SCHEMBL9003072 0.87 BCHE (0.40) SIRT2SIRT1CTSSCTSLBCHE
SCHEMBL9002812 0.87 F2 (0.40) CYP1A2SIRT2SIRT1CTSSCTSL
Hydrochloric Acid SCHEMBL9003079 0.86 F2 (0.40) CYP1A2SIRT2SIRT1CTSSCTSL
SCHEMBL9002951 0.86 CYP1A2 (0.41) CYP1A2CTSSTGM2CTSKCTSB
Hydrochloric Acid SCHEMBL9002908 0.85 CYP1A2 (0.41) CYP1A2CTSSTGM2CTSKCTSB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5559232-A ANTICOAGULANTS HOFFMANN-LA ROCHE INC. (US) 1996-09-24 US claimed
US-5559232-A ANTICOAGULANTS HOFFMANN-LA ROCHE INC. (US) 1996-09-24 US disclosed