Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 1/20 | 0.57 |
| ▸ | FAP | Q12884 | 1/20 | 0.57 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.44 |
| ▸ | XIAP | P98170 | 1/20 | 0.44 |
| ▸ | CMA1 | P23946 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 8/20 | 0.43 |
| ▸ | REN | P00797 | 4/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PEPD | P12955 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9622786 | 0.92 | PREP (0.49) | PREPFAPACE2XIAPCMA1 | |
| SCHEMBL11440574 | 0.90 | PREP (0.61) | PREPFAPACE2XIAPACE | |
| SCHEMBL9622782 | 0.88 | PREP (0.46) | PREPFAPACE2XIAPCMA1 | |
| SCHEMBL31181299 | 0.87 | CPA1 (0.47) | PREPFAPACE2XIAPACE | |
| SCHEMBL30708106 | 0.86 | CAPN1 (0.45) | PREPFAPACE2XIAPACE | |
| SCHEMBL11376449 | 0.85 | PREP (0.62) | PREPFAPACE2ACEREN | |
| SCHEMBL11376437 | 0.85 | PREP (0.62) | PREPFAPACE2ACEREN | |
| SCHEMBL10749197 | 0.85 | XIAP (0.49) | PREPFAPACE2XIAPCMA1 | |
| SCHEMBL10749206 | 0.85 | XIAP (0.49) | PREPFAPACE2XIAPCMA1 | |
| SCHEMBL8053385 | 0.84 | ACE (0.54) | PREPFAPACE2ACEREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0731841-A1 | PROTEASES FROM STREPTOMYCES AND USE THEREOF IN PROTEIN EXPRESSION SYSTEMS | Cangene Corporation (CA) | 1996-09-18 | — | — | EP | disclosed |
| WO-1995017512-A2 | PROTEASES FROM STREPTOMYCES AND USE THEREOF IN PROTEIN EXPRESSION SYSTEMS | CANGENE CORPORATION (CA) | 1995-06-29 | — | — | WO | disclosed |