Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 6/20 | 0.30 |
| ▸ | HTR1A | P08908 | 2/20 | 0.30 |
| ▸ | MAOA | P21397 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9268963 | 1.00 | SSTR4 (0.36) | SSTR4OPRM1HTR2AMAOBHTR1A | |
| Hydrochloric Acid SCHEMBL9002825 | 0.98 | SSTR4 (0.35) | SSTR4OPRM1HTR2AMAOB | |
| Hydrochloric Acid SCHEMBL9003158 | 0.98 | SSTR4 (0.35) | SSTR4OPRM1HTR2AMAOB | |
| Hydrochloric Acid SCHEMBL9267897 | 0.98 | SSTR4 (0.35) | SSTR4OPRM1HTR2AMAOB | |
| Hydrochloric Acid SCHEMBL9003453 | 0.98 | SSTR4 (0.35) | SSTR4OPRM1HTR2AMAOB | |
| SCHEMBL9002948 | 0.81 | SSTR4 (0.36) | SSTR4OPRM1HTR2AHTR1A | |
| SCHEMBL9003117 | 0.81 | SSTR4 (0.39) | SSTR4OPRM1HTR2AHTR1A | |
| SCHEMBL9275122 | 0.81 | SSTR4 (0.39) | SSTR4OPRM1HTR2AHTR1A | |
| SCHEMBL9003190 | 0.81 | SSTR4 (0.39) | SSTR4OPRM1HTR2AHTR1A | |
| SCHEMBL9003016 | 0.81 | SSTR4 (0.39) | SSTR4OPRM1HTR2AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5508433-A | Derivatives of perhydroisoindole and preparation thereof | RHONE-POULENC RORER S.A. (FR) | 1996-04-16 | — | — | US | claimed |
| US-5508433-A | Derivatives of perhydroisoindole and preparation thereof | RHONE-POULENC RORER S.A. (FR) | 1996-04-16 | — | — | US | disclosed |