SCHEMBL9003140

SCHEMBL9003140

CCOC(=O)CCN(C(=O)[C@H](CC(=O)NCC1CN(C(=N)N)CCO1)NC(=O)OCc1ccccc1)C1CC1

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
BCHE P06276 2/20 0.43
ACHE P22303 2/20 0.43
CACNA1F O60840 1/20 0.43
CACNA1D Q01668 1/20 0.43
CACNA1S Q13698 1/20 0.43
CACNA1C Q13936 1/20 0.43
F2 P00734 4/20 0.43
PRSS1 P07477 2/20 0.43
CYP1A2 P05177 1/20 0.41
TPSAB1 Q15661 1/20 0.39
TPSD1 Q9BZJ3 1/20 0.39
TPSG1 Q9NRR2 1/20 0.39
F10 P00742 1/20 0.37
CTSK P43235 4/20 0.37
SIRT2 Q8IXJ6 2/20 0.37
SIRT1 Q96EB6 1/20 0.37
CTSS P25774 3/20 0.36
CTSB P07858 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9003045 0.99 BCHE (0.43) BCHEACHECACNA1FCACNA1DCACNA1S
SCHEMBL9003152 0.93 CYP1A2 (0.42) F2PRSS1CYP1A2TPSAB1TPSD1
SCHEMBL9002766 0.90 BCHE (0.40) BCHEACHECACNA1FCACNA1DCACNA1S
Hydrochloric Acid SCHEMBL9002721 0.90 BCHE (0.40) BCHEACHECACNA1FCACNA1DCACNA1S
SCHEMBL7394423 0.89 BCHE (0.42) BCHEACHECACNA1FCACNA1DCACNA1S
Hydrochloric Acid SCHEMBL7391915 0.89 BCHE (0.42) BCHEACHECACNA1FCACNA1DCACNA1S
SCHEMBL9002966 0.88 CYP1A2 (0.42) F2PRSS1CYP1A2TPSAB1TPSD1
SCHEMBL9002887 0.88 F2 (0.48) BCHEACHECACNA1FCACNA1DCACNA1S
Hydrochloric Acid SCHEMBL9002915 0.87 CYP1A2 (0.42) F2PRSS1CYP1A2TPSAB1TPSD1
Hydrochloric Acid SCHEMBL9002599 0.87 F2 (0.49) BCHEACHECACNA1FCACNA1DCACNA1S

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5559232-A ANTICOAGULANTS HOFFMANN-LA ROCHE INC. (US) 1996-09-24 US disclosed