1,4-Dimethoxybenzene

1,4-Dimethoxybenzene

SCHEMBL9003907

COc1ccc(OC)cc1.O=C(N[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1n1ccc(=O)[nH]c1=O)C(F)(F)F

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SLC28A1 O00337 1/20 0.55
SLC28A2 O43868 1/20 0.55
SLC29A1 Q99808 1/20 0.55
SLC28A3 Q9HAS3 1/20 0.55
P2RY6 Q15077 4/20 0.51
P2RY2 P41231 6/20 0.49
P2RY4 P51582 3/20 0.49
P2RY14 Q15391 8/20 0.48
OGT O15294 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3491264 0.92 SLC28A1 (0.64) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL3491259 0.92 SLC28A1 (0.64) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL3491267 0.92 SLC28A1 (0.64) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL9547057 0.85 TYMP (0.48) P2RY6P2RY2P2RY4P2RY14
SCHEMBL15496787 0.85 SLC28A1 (0.59) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL15496786 0.85 SLC28A1 (0.61) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL7602561 0.85 P2RY6 (0.48) P2RY6P2RY2P2RY4P2RY14
SCHEMBL7094827 0.84 SLC28A1 (0.41) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL7094828 0.84 SLC28A1 (0.41) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL14565249 0.81 SLC28A1 (0.68) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0733058-A1 NUCLEIC ACID MEDIATED ELECTRON TRANSFER CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1996-09-25 EP disclosed
WO-1995015971-A2 NUCLEIC ACID MEDIATED ELECTRON TRANSFER CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1995-06-15 WO disclosed