Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | USP2 | O75604 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | APEX1 | P27695 | 2/20 | 0.60 |
| ▸ | RECQL | P46063 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | EGFR | P00533 | 1/20 | 0.60 |
| ▸ | FYN | P06241 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.60 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18472531 | 0.87 | BLM (0.69) | BLMKMT2AALDH1A1MEN1CYP1A2 | |
| SCHEMBL7564084 | 0.85 | SLC6A2 (0.57) | BLMKMT2AALDH1A1MEN1CYP1A2 | |
| SCHEMBL11333149 | 0.84 | BLM (0.65) | BLMKMT2AALDH1A1MEN1CYP1A2 | |
| SCHEMBL11333148 | 0.84 | BLM (0.65) | BLMKMT2AALDH1A1MEN1CYP1A2 | |
| Racemetyrosine SCHEMBL61871 | 0.83 | BLM (1.00) | BLMKMT2AALDH1A1MEN1CYP1A2 | |
| SCHEMBL6717499 | 0.83 | BLM (0.73) | BLMKMT2AALDH1A1MEN1CYP1A2 | |
| Metyrosine SCHEMBL50398 | 0.83 | BLM (1.00) | BLMKMT2AALDH1A1MEN1CYP1A2 | |
| Hydrochloric Acid SCHEMBL11335298 | 0.83 | BLM (0.73) | BLMKMT2AALDH1A1MEN1CYP1A2 | |
| SCHEMBL6717498 | 0.83 | BLM (0.73) | BLMKMT2AALDH1A1MEN1CYP1A2 | |
| SCHEMBL15218062 | 0.83 | BLM (0.73) | BLMKMT2AALDH1A1MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733037-A1 | ARYL SUBSTITUTED AMINO ACIDS, CNS INFLUENCING AGENTS | UNIVERSITY OF BRISTOL (GB) | 1996-09-25 | — | — | EP | disclosed |
| WO-1995015941-A1 | ARYL SUBSTITUTED AMINO ACIDS, CNS INFLUENCING AGENTS | UNIVERSITY OF BRISTOL (GB) | 1995-06-15 | — | — | WO | disclosed |