Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.70 |
| ▸ | APEX1 | P27695 | 1/20 | 0.70 |
| ▸ | HTT | P42858 | 1/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 4/20 | 0.64 |
| ▸ | NPC1 | O15118 | 3/20 | 0.64 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.64 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.64 |
| ▸ | RELA | Q04206 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20777010 | 0.99 | POLB (0.68) | POLBAPEX1HTTTDP1LMNA | |
| SCHEMBL13572525 | 0.96 | POLB (0.65) | POLBAPEX1HTTTDP1LMNA | |
| SCHEMBL16921471 | 0.96 | POLB (0.75) | POLBAPEX1HTTTDP1LMNA | |
| SCHEMBL14097952 | 0.95 | POLB (0.72) | POLBAPEX1HTTTDP1LMNA | |
| SCHEMBL21286708 | 0.94 | POLB (0.71) | POLBAPEX1HTTTDP1LMNA | |
| SCHEMBL1532227 | 0.93 | POLB (0.61) | POLBAPEX1HTTTDP1LMNA | |
| SCHEMBL223942 | 0.93 | POLB (0.61) | POLBAPEX1HTTTDP1LMNA | |
| SCHEMBL13572529 | 0.93 | POLB (0.61) | POLBAPEX1HTTTDP1LMNA | |
| SCHEMBL12768436 | 0.93 | POLB (0.61) | POLBAPEX1HTTTDP1LMNA | |
| SCHEMBL12768640 | 0.93 | POLB (0.61) | POLBAPEX1HTTTDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543267-A | Photo-induced optically anisotropic amorphous film materials from side group polymers | AGFA-GEVAERT AG (DE) | 1996-08-06 | — | — | US | disclosed |