⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2375897 | 0.78 | — | — | |
| SCHEMBL10757433 | 0.75 | — | — | |
| SCHEMBL8475271 | 0.75 | — | — | |
| SCHEMBL631418 | 0.71 | — | — | |
| SCHEMBL631416 | 0.71 | — | — | |
| SCHEMBL19307242 | 0.71 | — | — | |
| SCHEMBL12099018 | 0.69 | — | — | |
| SCHEMBL3030245 | 0.69 | — | — | |
| SCHEMBL11406879 | 0.69 | — | — | |
| SCHEMBL2234666 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563084-A | Novel trifluoromethylpropionamide derivatives as HTRA1 inhibitors | 豪夫迈·罗氏有限公司 | 2019-04-02 | — | — | CN | claimed |
| CN-107207421-A | New trifluoromethyl propanamide derivative | 豪夫迈·罗氏有限公司 | 2017-09-26 | — | — | CN | claimed |
| EP-3072178-B1 | USE OF LITHIUM BIS(FLUOROSULFONYL) IMIDE (LIFSI) IN NON-AQUEOUS ELECTROLYTE SOLUTIONS FOR USE WITH 4.2V AND HIGHER CATHODE MATERIALS FOR LITHIUM ION BATTERIES | SHENZHEN CAPCHEM TECHNOLOGY CO LTD (CN) | 2019-04-10 | — | — | EP | disclosed |
| CN-109563084-A | Novel trifluoromethylpropionamide derivatives as HTRA1 inhibitors | 豪夫迈·罗氏有限公司 | 2019-04-02 | — | — | CN | disclosed |
| CN-108699106-A | Novel trifluoromethyl propanamide derivative as HTRA1 inhibitor | 豪夫迈·罗氏有限公司 | 2018-10-23 | — | — | CN | disclosed |
| CN-104981934-B | Non-aqueous electrolyte solution and electrochemical cell comprising the same | 深圳新宙邦科技股份有限公司 | 2018-06-08 | — | — | CN | disclosed |
| CN-107207421-A | New trifluoromethyl propanamide derivative | 豪夫迈·罗氏有限公司 | 2017-09-26 | — | — | CN | disclosed |
| US-20170027173-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, LLC (US) | 2017-02-02 | — | — | US | disclosed |
| US-9499524-B2 | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2016-11-22 | — | — | US | disclosed |
| US-20160302414-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2016-10-20 | — | — | US | disclosed |
| EP-3072178-A1 | USE OF LITHIUM BIS(FLUOROSULFONYL) IMIDE (LIFSI) IN NON-AQUEOUS ELECTROLYTE SOLUTIONS FOR USE WITH 4.2V AND HIGHER CATHODE MATERIALS FOR LITHIUM ION BATTERIES | BASF Corporation (US) | 2016-09-28 | — | — | EP | disclosed |
| US-20130012547-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2013-01-10 | — | — | US | disclosed |
| EP-2520570-A1 | AMINOPYRIDINE COMPOUND | Ube Industries, Ltd. (JP) | 2012-11-07 | — | — | EP | disclosed |
| US-20120259123-A1 | AMINOPYRIDINE COMPOUND | UBE INDUSTRIES, LTD. (JP) | 2012-10-11 | — | — | US | disclosed |
| WO-2012116277-A1 | CANNABINOID RECEPTOR MODULATORS | ARENA PHARMACEUTICALS, INC. (US) | 2012-08-30 | — | — | WO | disclosed |
| EP-0442097-B1 | Poly(arylenevinylene siloxanes) | CONSORTIUM ELEKTROCHEM IND (DE) | 1996-10-09 | — | — | EP | disclosed |
| EP-0582615-B1 | POLYIMIDE SILOXANES WHICH ALSO INCLUDE ESTER AND/OR AMIDE GROUPS | CONSORTIUM ELEKTROCHEM IND (DE) | 1995-06-28 | — | — | EP | disclosed |
| EP-0582615-A1 | POLYIMIDE SILOXANES WHICH ALSO INCLUDE ESTER AND/OR AMIDE GROUPS. | CONSORTIUM ELEKTROCHEM IND (DE) | 1994-02-16 | — | — | EP | disclosed |
| WO-1992019668-A1 | POLYIMIDE SILOXANES WHICH ALSO INCLUDE ESTER AND/OR AMIDE GROUPS | CONSORTIUM FÜR ELEKTRO-CHEMISCHE INDUSTRIE GMBH (DE) | 1992-11-12 | — | — | WO | disclosed |
| EP-0442097-A2 | Poly(arylenevinylene siloxanes) | Consortium für elektrochemische Industrie GmbH (DE) | 1991-08-21 | — | — | EP | disclosed |