Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 8/20 | 0.53 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7778589 | 0.92 | PTGIR (0.49) | PTGIRTBXAS1ALDH1A1KDM4EMEN1 | |
| SCHEMBL8411209 | 0.88 | PTGIR (0.56) | PTGIRTBXAS1 | |
| SCHEMBL9155513 | 0.84 | PTGIR (0.69) | PTGIRTBXAS1 | |
| SCHEMBL9005581 | 0.84 | PTGIR (0.70) | PTGIRTBXAS1 | |
| SCHEMBL7772386 | 0.83 | PTGIR (0.54) | PTGIRTBXAS1 | |
| SCHEMBL8414336 | 0.82 | PTGIR (0.49) | PTGIRTBXAS1 | |
| SCHEMBL8414245 | 0.82 | PTGIR (0.57) | PTGIR | |
| SCHEMBL8411211 | 0.81 | PTGIR (0.47) | PTGIR | |
| SCHEMBL7483364 | 0.80 | USP2 (0.45) | ALDH1A1KDM4EMEN1MAPTHPGD | |
| SCHEMBL8413684 | 0.80 | PTGIR (0.57) | PTGIRTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0578847-B1 | Fused benzeneoxyacetic acid derivatives and their use as PG12 antagonists | ONO PHARMACEUTICAL CO (JP) | 1996-10-09 | — | — | EP | disclosed |
| US-5461045-A | Treating thrombosis, arteriosclerosis, ischemic heart diseases, gastric ulcer and hypertension | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-10-24 | — | — | US | disclosed |
| EP-0578847-A1 | Fused benzeneoxyacetic acid derivatives and their use as PG12 antagonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-01-19 | — | — | EP | disclosed |