⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21477434 | 0.67 | — | — | |
| SCHEMBL19373666 | 0.64 | — | — | |
| SCHEMBL7339718 | 0.61 | — | — | |
| SCHEMBL19046592 | 0.56 | — | — | |
| SCHEMBL15910073 | 0.53 | CYP2C19 (0.33) | — | |
| SCHEMBL5405661 | 0.53 | — | — | |
| SCHEMBL12410331 | 0.53 | CYP2C19 (0.33) | — | |
| SCHEMBL14557461 | 0.53 | CYP2C19 (0.33) | — | |
| SCHEMBL1329478 | 0.50 | — | — | |
| SCHEMBL31414726 | 0.47 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0493788-B1 | Three-layer vascular prosthesis | MUDR MILAN KRAJICEK CSC (CS) | 1996-09-25 | — | — | EP | disclosed |
| US-5413597-A | Three-layer vascular prostheses | KRAJICEK MILAN (CS) | 1995-05-09 | — | — | US | disclosed |
| EP-0493788-A1 | Three-layer vascular prosthesis | MUDR. MILAN KRAJICEK CSc. (CS) | 1992-07-08 | — | — | EP | disclosed |