Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | CASR | P41180 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CCKBR | P32239 | 2/20 | 0.35 |
| ▸ | PRMT3 | O60678 | 3/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | CMA1 | P23946 | 3/20 | 0.35 |
| ▸ | CTRC | Q99895 | 2/20 | 0.35 |
| ▸ | CCR3 | P51677 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9005830 | 0.88 | CASR (0.37) | EPHX2CASRCCKBRCCR3NPC1 | |
| SCHEMBL9005817 | 0.84 | CA12 (0.38) | EPHX2CASRCCKBRNPC1MITF | |
| SCHEMBL9005838 | 0.81 | CASR (0.35) | EPHX2CASRCCKBRCMA1CTRC | |
| SCHEMBL5274728 | 0.81 | CASR (0.40) | CASRCCKBRNPC1MITFRAB9A | |
| SCHEMBL8871088 | 0.81 | CASR (0.40) | CASRCCKBRNPC1MITFRAB9A | |
| SCHEMBL8876778 | 0.81 | CASR (0.40) | CASRCCKBRNPC1MITFRAB9A | |
| SCHEMBL7577139 | 0.81 | CASR (0.40) | CASRCCKBRNPC1MITFRAB9A | |
| SCHEMBL7572233 | 0.79 | MEN1 (0.42) | EPHX2CASRALDH1A1CCKBRNPC1 | |
| SCHEMBL5276625 | 0.79 | MEN1 (0.42) | EPHX2CASRALDH1A1CCKBRNPC1 | |
| SCHEMBL8870860 | 0.79 | CASR (0.42) | USP30EPHX2CASRALDH1A1CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0678089-B1 | N-ACYL PYRROLIDINES AND DRUGS FOR THE TREATMENT OR PREVENTION OF CHOLECYSTOKININ AND GASTRIN-RELATED DISORDERS | RHONE POULENC RORER SA (FR) | 1996-10-09 | — | — | EP | claimed |