SCHEMBL9005873

SCHEMBL9005873

CCCCCCCCCCCCCCCCCCCCCCC(N)(CCCCCCCCCCCCCCCCCCCCCC)c1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SCN5A Q14524 3/20 0.41
SCN9A Q15858 3/20 0.41
SIGMAR1 Q99720 2/20 0.40
EBP Q15125 1/20 0.40
CNR1 P21554 1/20 0.40
CNR2 P34972 1/20 0.40
KIF11 P52732 3/20 0.39
KCNN4 O15554 1/20 0.39
TNNC1 P63316 5/20 0.39
SGPL1 O95470 1/20 0.39
S1PR4 O95977 1/20 0.39
S1PR1 P21453 1/20 0.39
GPR183 P32249 1/20 0.39
CERS2 Q96G23 1/20 0.39
S1PR3 Q99500 1/20 0.39
S1PR5 Q9H228 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1262316 1.00 SCN5A (0.41) SCN5ASCN9ASIGMAR1EBPCNR1
SCHEMBL9005884 1.00 SCN5A (0.41) SCN5ASCN9ASIGMAR1EBPCNR1
SCHEMBL1260763 1.00 SCN5A (0.41) SCN5ASCN9ASIGMAR1EBPCNR1
SCHEMBL19513936 1.00 SCN5A (0.41) SCN5ASCN9ASIGMAR1EBPCNR1
SCHEMBL3453397 1.00 SCN5A (0.41) SCN5ASCN9ASIGMAR1EBPCNR1
SCHEMBL1262237 1.00 SCN5A (0.41) SCN5ASCN9ASIGMAR1EBPCNR1
SCHEMBL1260667 1.00 SCN5A (0.41) SCN5ASCN9ASIGMAR1EBPCNR1
SCHEMBL1262352 1.00 SCN5A (0.41) SCN5ASCN9ASIGMAR1EBPCNR1
Hydrochloric Acid SCHEMBL28488727 0.98 SCN5A (0.40) SCN5ASCN9ASIGMAR1EBPCNR1
SCHEMBL11325146 0.98 KCNN4 (0.41) SCN5ASCN9ASIGMAR1EBPCNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5540850-A ANIONIC SURFACTANTS, CATIONIC SURFACTANTS, CELLULOSE ETHERS AND NONIONIC SURFACTANTS LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1996-07-30 US disclosed
EP-0320296-B1 Fabric softening additive for detergent compositions UNILEVER PLC (GB) 1994-03-16 EP disclosed
US-5160641-A Soaps, fatty amines, clays LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1992-11-03 US disclosed
EP-0026528-B2 DETERGENT COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1992-08-19 EP disclosed
US-5128055-A Softener, cellulose ether LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1992-07-07 US disclosed
US-5009800-A Particle mixture LEVER BROTHERS COMPANY, DIVISION OF CONOPCO INC. (US) 1991-04-23 US disclosed
US-4970028-A FATTY AMINE, NONIONIC SURFACTANT LEVER BROTHERS COMPANY (US) 1990-11-13 US disclosed
EP-0276999-B1 FABRIC CONDITIONING COMPOSITION UNILEVER PLC (GB) 1990-10-31 EP disclosed
EP-0309264-A2 A composition for softening fabrics UNILEVER PLC (GB) 1989-03-29 EP disclosed
EP-0213730-B1 DETERGENT COMPOSITION WITH FABRIC SOFTENING PROPERTIES UNILEVER PLC (GB) 1988-11-09 EP disclosed
US-4615815-A SODIUM PERBORATE MONOHYDRATE AS ABSORBER OF TERT-AMINE, PHOSPHONIUM OR SULFONIUM SOFTENING AGENT LEVER BROTHERS COMPANY (US) 1986-10-07 US disclosed
EP-0120528-B1 DETERGENT COMPOSITIONS UNILEVER N.V. (NL) 1986-06-25 EP disclosed
EP-0137533-A1 Free-flowing particulate fabric-softening adjunct for use in laundry detergent compositions and method of making same UNILEVER N.V. (NL) 1985-04-17 EP disclosed
EP-0026528-B1 DETERGENT COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1984-12-05 EP disclosed
EP-0023367-B1 DETERGENT COMPOSITION HAVING TEXTILE SOFTENING PROPERTY THE PROCTER & GAMBLE COMPANY (US) 1984-11-07 EP disclosed
US-4479881-A Detergent compositions LEVER BROTHERS COMPANY (US) 1984-10-30 US disclosed
EP-0120528-A1 Detergent compositions UNILEVER N.V. (NL) 1984-10-03 EP disclosed
US-4338204-A Detergent softener containing anionic, amine, and water soluble cationic THE PROCTER & GAMBLE COMPANY (US) 1982-07-06 US disclosed
US-4294710-A ANIONIC SURFACTANTS, BUILDER SALTS, ALKYLAMINES OR IMIDAZOLES THE PROCTER & GAMBLE COMPANY (US) 1981-10-13 US disclosed
EP-0023367-A1 Detergent composition having textile softening property THE PROCTER & GAMBLE COMPANY (US) 1981-02-04 EP disclosed