SCHEMBL900595

SCHEMBL900595

[Ru]C1(P(c2ccccc2)c2ccccc2)C=Cc2ccccc2C1c1c(P(c2ccccc2)c2ccccc2)ccc2ccccc12

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9818123 0.92
SCHEMBL1943136 0.84
SCHEMBL1905021 0.84
Hydrochloric Acid SCHEMBL20481635 0.83
Hydrochloric Acid SCHEMBL125218 0.83
SCHEMBL8729098 0.81
SCHEMBL22406221 0.81
Perchlorate SCHEMBL5454038 0.81
SCHEMBL4047529 0.79
Acetic Acid SCHEMBL6600577 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2531486-B1 NOVEL PROCESS FOR THE PREPARATION OF NITROGEN SUBSTITUTED AMINOTETRALINS DERIVATIVES UCB BIOPHARMA SPRL (BE) 2017-06-21 EP claimed
US-8969620-B2 Process for the preparation of amino acid derivatives UCB PHARMA GMBH (DE) 2015-03-03 US claimed
US-8729306-B2 Process for the preparation of nitrogen substituted aminotetralins derivatives UCB PHARMA GMBH (DE) 2014-05-20 US claimed
EP-2621893-A1 PROCESS FOR THE PREPARATION OF AMINO ACID DERIVATIVES UCB Pharma GmbH (DE) 2013-08-07 EP claimed
US-20130190533-A1 PROCESS FOR THE PREPARATION OF AMINO ACID DERIVATIVES UCB PHARMA GMBH (DE) 2013-07-25 US claimed
EP-2531486-A2 NOVEL PROCESS FOR THE PREPARATION OF NITROGEN SUBSTITUTED AMINOTETRALINS DERIVATIVES UCB Pharma GmbH (DE) 2012-12-12 EP claimed
US-20120302790-A1 Novel Process for the Preparation of Nitrogen Substituted Aminotetralins Derivatives UCB PHARMA, S.A. (BE) 2012-11-29 US claimed
WO-2012041986-A1 PROCESS FOR THE PREPARATION OF AMINO ACID DERIVATIVES UCB PHARMA GMBH (DE) 2012-04-05 WO claimed
WO-2011095539-A2 NOVEL PROCESS FOR THE PREPARATION OF NITROGEN SUBSTITUTED AMINOTETRALINS DERIVATIVES UCB PHARMA GMBH (DE) 2011-08-11 WO claimed
EP-0275354-B1 PROCESS FOR PREPARING OPTICALLY ACTIVE ARYLACETIC ACID DERIVATIVES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-10-16 EP claimed
US-20180356725-A1 RADIATION-SENSITIVE COMPOSITION AND PATTERN-FORMING METHOD JSR CORPORATION (JP) 2018-12-13 US disclosed
EP-2531486-B1 NOVEL PROCESS FOR THE PREPARATION OF NITROGEN SUBSTITUTED AMINOTETRALINS DERIVATIVES UCB BIOPHARMA SPRL (BE) 2017-06-21 EP disclosed
US-8969620-B2 Process for the preparation of amino acid derivatives UCB PHARMA GMBH (DE) 2015-03-03 US disclosed
US-8729306-B2 Process for the preparation of nitrogen substituted aminotetralins derivatives UCB PHARMA GMBH (DE) 2014-05-20 US disclosed
EP-2621893-A1 PROCESS FOR THE PREPARATION OF AMINO ACID DERIVATIVES UCB Pharma GmbH (DE) 2013-08-07 EP disclosed
US-6034239-A BINDIG TO MELATONIN RECEPTORS; SLEEP DISORDERS; GLANDULAR DISORDERS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2000-03-07 US disclosed
EP-0885210-A1 Tricylic compounds having binding affinity for melatonin receptors, their production and use Takeda Chemical Industries, Ltd. (JP) 1998-12-23 EP disclosed
EP-0795328-A1 Use of naphthalene derivatives in treating lung carcinoma PFIZER INC. (US) 1997-09-17 EP disclosed
WO-1997032871-A1 TRICYCLIC COMPOUNDS, THEIR PRODUCTION AND USE TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1997-09-12 WO disclosed
EP-0275354-B1 PROCESS FOR PREPARING OPTICALLY ACTIVE ARYLACETIC ACID DERIVATIVES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-10-16 EP disclosed