Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 13/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2345217 | 1.00 | EPHX1 (0.43) | EPHX1ACHEALDH1A1NPC1RAB9A | |
| SCHEMBL4778608 | 0.87 | CA1 (0.41) | EPHX1ACHEALDH1A1 | |
| SCHEMBL1696818 | 0.86 | CA1 (0.46) | EPHX1ACHEALDH1A1NPC1RAB9A | |
| SCHEMBL20683487 | 0.86 | CA1 (0.46) | EPHX1ACHEALDH1A1NPC1RAB9A | |
| SCHEMBL2344660 | 0.85 | EPHX1 (0.44) | EPHX1ACHEALDH1A1NPC1RAB9A | |
| SCHEMBL5199004 | 0.83 | EPHX1 (0.43) | EPHX1ACHEALDH1A1NPC1RAB9A | |
| SCHEMBL7372859 | 0.83 | EPHX1 (0.43) | EPHX1ACHEALDH1A1NPC1RAB9A | |
| SCHEMBL4727557 | 0.83 | EPHX1 (0.43) | EPHX1ACHEALDH1A1NPC1RAB9A | |
| SCHEMBL5782797 | 0.83 | EPHX1 (0.43) | EPHX1ACHEALDH1A1NPC1RAB9A | |
| SCHEMBL7453134 | 0.83 | EPHX1 (0.43) | EPHX1ACHEALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3541789-A1 | ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS | Boehringer Ingelheim Animal Health USA Inc. (US) | 2019-09-25 | — | — | EP | disclosed |
| WO-2018093920-A1 | ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS | MERIAL, INC. (US) | 2018-05-24 | — | — | WO | disclosed |
| EP-3298027-A1 | ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS | Merial, Inc. (US) | 2018-03-28 | — | — | EP | disclosed |
| WO-2016187534-A1 | ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS | MERIAL, INC. (US) | 2016-11-24 | — | — | WO | disclosed |
| EP-0736032-A1 | HETEROCYCLIC COMPOUNDS | Astra Aktiebolag (SE) | 1996-10-09 | — | — | EP | disclosed |
| WO-1995017410-A1 | HETEROCYCLIC COMPOUNDS | ASTRA AKTIEBOLAG (SE) | 1995-06-29 | — | — | WO | disclosed |