SCHEMBL9006431

SCHEMBL9006431

CC(=O)c1ccc(C(C)=Cc2ccc(OC(F)=C(F)F)cc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.45
ESR2 Q92731 1/20 0.45
KMT2A Q03164 4/20 0.44
MAPT P10636 2/20 0.43
RAB9A P51151 2/20 0.43
HPGD P15428 1/20 0.43
NQO2 P16083 5/20 0.42
PTGS1 P23219 3/20 0.41
PTGS2 P35354 3/20 0.41
NPSR1 Q6W5P4 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.38
TUBB1 Q9H4B7 1/20 0.38
NPC1 O15118 1/20 0.38
GAA P10253 1/20 0.38
LMNA P02545 1/20 0.38
GLA P06280 1/20 0.38
TSHR P16473 1/20 0.38
RARB P10826 2/20 0.37
RARG P13631 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9006426 1.00 ESR1 (0.45) ESR1ESR2KMT2AMAPTRAB9A
SCHEMBL8935004 0.92 ESR1 (0.52) ESR1ESR2MAPTRAB9AHPGD
SCHEMBL8935002 0.92 ESR1 (0.52) ESR1ESR2MAPTRAB9AHPGD
SCHEMBL9006553 0.90 RARG (0.48) ESR1ESR2RAB9ANPSR1L3MBTL1
SCHEMBL9006510 0.90 RARG (0.48) ESR1ESR2RAB9ANPSR1L3MBTL1
SCHEMBL9006501 0.90 RARG (0.48) ESR1ESR2RAB9ANPSR1L3MBTL1
SCHEMBL9006561 0.90 RARG (0.48) ESR1ESR2RAB9ANPSR1L3MBTL1
SCHEMBL9006649 0.87 PTGS1 (0.48) ESR1ESR2KMT2AMAPTHPGD
SCHEMBL9006522 0.87 NQO2 (0.58) ESR1ESR2KMT2AMAPTHPGD
SCHEMBL9006606 0.87 PTGS1 (0.48) ESR1ESR2KMT2AMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5489623-A APPLYING POLYMER TO SURFACE, EXPOSING TO INCIDENT PHOTONICRADIATION TO RENDER PORTIONS LESS SOLUBLE OR DISPERSIBLE THE DOW CHEMICAL COMPANY (US) 1996-02-06 US claimed
EP-0676062-A1 PHOTODEFINABLE POLYMERS CONTAINING PERFLUOROCYCLOBUTANE GROUPS THE DOW CHEMICAL COMPANY (US) 1995-10-11 EP claimed
US-5426164-A Solvent and chemical resistant coatings and photoresists; photocuring of perfluorovinyl polymers containing photo active sites; cyclization THE DOW CHEMICAL COMPANY (US) 1995-06-20 US claimed
WO-1994015258-A1 PHOTODEFINABLE POLYMERS CONTAINING PERFLUOROCYCLOBUTANE GROUPS THE DOW CHEMICAL COMPANY (US) 1994-07-07 WO claimed
US-5489623-A APPLYING POLYMER TO SURFACE, EXPOSING TO INCIDENT PHOTONICRADIATION TO RENDER PORTIONS LESS SOLUBLE OR DISPERSIBLE THE DOW CHEMICAL COMPANY (US) 1996-02-06 US disclosed
EP-0676062-A1 PHOTODEFINABLE POLYMERS CONTAINING PERFLUOROCYCLOBUTANE GROUPS THE DOW CHEMICAL COMPANY (US) 1995-10-11 EP disclosed
US-5426164-A Solvent and chemical resistant coatings and photoresists; photocuring of perfluorovinyl polymers containing photo active sites; cyclization THE DOW CHEMICAL COMPANY (US) 1995-06-20 US disclosed
WO-1994015258-A1 PHOTODEFINABLE POLYMERS CONTAINING PERFLUOROCYCLOBUTANE GROUPS THE DOW CHEMICAL COMPANY (US) 1994-07-07 WO disclosed