SCHEMBL9007262

SCHEMBL9007262

Oc1ccc(-c2nc3ccccc3n2-c2ccc(-n3c(-c4ccc(O)cc4)nc4ccccc43)cc2)cc1

nearest known ligand 0.91

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 5/20 0.91
ESR1 P03372 5/20 0.91
GRIA1 P42261 1/20 0.86
CACNG8 Q8WXS5 1/20 0.86
CACNG2 Q9Y698 1/20 0.86
ALDH1A1 P00352 2/20 0.59
PTGS2 P35354 1/20 0.56
RECQL P46063 1/20 0.49
MAPK1 P28482 1/20 0.49
HTT P42858 1/20 0.49
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
KDM4E B2RXH2 1/20 0.47
NPC1 O15118 1/20 0.47
LMNA P02545 1/20 0.47
RAB9A P51151 1/20 0.47
FGFR1 P11362 2/20 0.46
HDAC1 Q13547 1/20 0.46
HDAC8 Q9BY41 1/20 0.46
HDAC6 Q9UBN7 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6440249 1.00 ESR2 (0.91) ESR2ESR1GRIA1CACNG8CACNG2
SCHEMBL13400666 0.98 ESR2 (0.88) ESR2ESR1GRIA1CACNG8CACNG2
SCHEMBL6440186 0.95 ESR2 (1.00) ESR2ESR1GRIA1CACNG8CACNG2
SCHEMBL8021778 0.95 ESR2 (0.88) ESR2ESR1GRIA1CACNG8CACNG2
SCHEMBL10047632 0.94 ESR2 (0.85) ESR2ESR1GRIA1CACNG8CACNG2
SCHEMBL6462714 0.93 ESR2 (0.78) ESR2ESR1GRIA1CACNG8CACNG2
SCHEMBL6460972 0.89 ESR2 (0.72) ESR2ESR1GRIA1CACNG8CACNG2
SCHEMBL6454533 0.89 ESR2 (0.72) ESR2ESR1GRIA1CACNG8CACNG2
SCHEMBL7061814 0.89 ESR2 (0.77) ESR2ESR1GRIA1CACNG8CACNG2
SCHEMBL6445980 0.88 ESR2 (0.71) ESR2ESR1GRIA1CACNG8CACNG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5554715-A DI/HYDROXYPHENYL-N-ARYLENEBENZIMIDAZOLES/ USED AS MONOMERS IN THE DISPLACEMENT REACTION ARE CLAIMED. THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 1996-09-10 US disclosed
US-5410012-A Poly(N-arylenebenzimidazoles) via aromatic nucleophilic displacement THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 1995-04-25 US disclosed