Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL9007433

N.N.Nc1ccc(Cc2cccc(N)c2)cc1

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 3/20 0.67
CYP3A4 P08684 4/20 0.61
ALDH1A1 P00352 1/20 0.61
TSHR P16473 1/20 0.61
TDP1 Q9NUW8 1/20 0.61
CA1 P00915 1/20 0.57
CA2 P00918 1/20 0.57
CA9 Q16790 1/20 0.57
MAOB P27338 6/20 0.52
MAOA P21397 4/20 0.52
CYP17A1 P05093 2/20 0.49
CYP11B1 P15538 2/20 0.49
CYP11B2 P19099 2/20 0.49
LOXL2 Q9Y4K0 1/20 0.46
CASP1 P29466 1/20 0.46
RECQL P46063 1/20 0.46
GFER P55789 1/20 0.42
PARP1 P09874 1/20 0.42
IDH1 O75874 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29929353 0.98 CYP19A1 (0.69) CYP19A1CYP3A4ALDH1A1TSHRTDP1
4,4'-Methylenedianiline SCHEMBL20917783 0.98 CYP19A1 (0.69) CYP19A1CYP3A4ALDH1A1TSHRTDP1
SCHEMBL16443297 0.98 CYP19A1 (0.69) CYP19A1CYP3A4ALDH1A1TSHRTDP1
SCHEMBL125532 0.98 CYP19A1 (0.69) CYP19A1CYP3A4ALDH1A1TSHRTDP1
Hydrochloric Acid SCHEMBL10938880 0.96 CYP19A1 (0.67) CYP19A1CYP3A4ALDH1A1TSHRTDP1
SCHEMBL29569468 0.96 CYP19A1 (0.67) CYP19A1CYP3A4ALDH1A1TSHRTDP1
Hydrochloric Acid SCHEMBL8642012 0.96 CYP19A1 (0.67) CYP19A1CYP3A4ALDH1A1TSHRTDP1
SCHEMBL18045557 0.96 CYP19A1 (0.67) CYP19A1CYP3A4ALDH1A1TSHRTDP1
SCHEMBL3482569 0.93 CA1 (0.62) CYP19A1CYP3A4ALDH1A1TSHRTDP1
SCHEMBL9719373 0.93 CA1 (0.62) CYP19A1CYP3A4ALDH1A1TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0583958-B1 Polyimide/aliphatic polyester copolymers EXXON RESEARCH ENGINEERING CO (US) 1996-10-02 EP claimed