Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 2/20 | 0.60 |
| ▸ | NOS2 | P35228 | 8/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | APEX1 | P27695 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | BLM | P54132 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
| ▸ | ARG2 | P78540 | 4/20 | 0.54 |
| ▸ | ARG1 | P05089 | 3/20 | 0.54 |
| ▸ | NOS1 | P29475 | 6/20 | 0.53 |
| ▸ | NOS3 | P29474 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | GRM8 | O00222 | 1/20 | 0.52 |
| ▸ | GRM6 | O15303 | 1/20 | 0.52 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9007740 | 1.00 | GSR (0.60) | GSRNOS2CYP1A2CYP2C19TSHR | |
| SCHEMBL3954319 | 1.00 | GSR (0.60) | GSRNOS2CYP1A2CYP2C19TSHR | |
| Hydrochloric Acid SCHEMBL10420618 | 0.98 | GSR (0.58) | GSRNOS2CYP1A2CYP2C19TSHR | |
| SCHEMBL15778941 | 0.90 | KMT2A (0.61) | GSRNOS2CYP1A2CYP2C19TSHR | |
| SCHEMBL15778940 | 0.90 | KMT2A (0.61) | GSRNOS2CYP1A2CYP2C19TSHR | |
| SCHEMBL15778942 | 0.90 | KMT2A (0.61) | GSRNOS2CYP1A2CYP2C19TSHR | |
| SCHEMBL29289 | 0.89 | GSR (0.71) | GSRNOS2CYP1A2CYP2C19TSHR | |
| SCHEMBL10135848 | 0.89 | GSR (0.71) | GSRNOS2CYP1A2CYP2C19TSHR | |
| SCHEMBL29387596 | 0.89 | GSR (0.71) | GSRNOS2CYP1A2CYP2C19TSHR | |
| SCHEMBL29291 | 0.89 | GSR (0.71) | GSRNOS2CYP1A2CYP2C19TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0593491-B1 | LUTEINIZING HORMONE RELEASING HORMONE ANTAGONIST PEPTIDES | DEGHENGHI ROMANO (CH) | 1996-10-23 | — | — | EP | claimed |